MOPED enables discoveries through consistently processed proteomics data.
MOPED enables discoveries through consistently processed proteomics data.
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DOI：
10.1021/pr400884c
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发表时间：
2014-01-03
影响因子：
4.4
通讯作者：
Kolker E
中科院分区：
文献类型：
--
作者：
Higdon R;Stewart E;Stanberry L;Haynes W;Choiniere J;Montague E;Anderson N;Yandl G;Janko I;Broomall W;Fishilevich S;Lancet D;Kolker N;Kolker E
模型生物蛋白质表达数据库（MOPED，http://moped.proteinspire.org）是一个不断扩展的蛋白质组学资源，可用于生物和生物医学发现。MOPED汇集了来自人类和模式生物（小鼠、蠕虫和酵母）的蛋白质组学（质谱）实验的蛋白质表达和元数据的简单、标准化和一致处理的摘要。最新版本的MOPED增加了对蛋白质丰度和浓度的新估计，以及相对（差异）表达数据。MOPED提供了一个新的更新的查询界面，允许用户通过生物体，组织，定位，条件，实验或关键字来探索信息。MOPED支持人类蛋白质组计划的努力，通过提供从蛋白质到染色体和疾病信息的链接以及许多互补资源来生成染色体和疾病特异性蛋白质组。MOPED支持一个新的组学元数据清单，以协调数据整合、分析和使用。MOPED的开发由用户社区推动，该社区遍布90个国家/地区，指导未来的开发，将MOPED转变为多组学资源。MOPED鼓励用户以简单的格式提交数据。他们可以使用元数据检查表为这次提交生成数据发布.因此，MOPED将为复杂的生物过程和系统提供更深入的见解，并实现更深入，更全面的生物和生物医学发现。
The Model Organism Protein Expression Database (MOPED, http://moped.proteinspire.org), is an expanding proteomics resource to enable biological and biomedical discoveries. MOPED aggregates simple, standardized and consistently processed summaries of protein expression and metadata from proteomics (mass spectrometry) experiments from human and model organisms (mouse, worm and yeast). The latest version of MOPED adds new estimates of protein abundance and concentration, as well as relative (differential) expression data. MOPED provides a new updated query interface that allows users to explore information by organism, tissue, localization, condition, experiment, or keyword. MOPED supports the Human Proteome Project’s efforts to generate chromosome and diseases specific proteomes by providing links from proteins to chromosome and disease information, as well as many complementary resources. MOPED supports a new omics metadata checklist in order to harmonize data integration, analysis and use. MOPED’s development is driven by the user community, which spans 90 countries guiding future development that will transform MOPED into a multi-omics resource. MOPED encourages users to submit data in a simple format. They can use the metadata a checklist generate a data publication for this submission. As a result, MOPED will provide even greater insights into complex biological processes and systems and enable deeper and more comprehensive biological and biomedical discoveries.
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影响因子：
4.3
作者：
Haynes WA;Higdon R;Stanberry L;Collins D;Kolker E
通讯作者：
Kolker E
影响因子：
4.4
作者：
Fanayan, Susan;Smith, Joshua T.;Nice, Edouard
通讯作者：
Nice, Edouard
影响因子：
3.3
作者：
Higdon, Roger;Reiter, Lukas;Kolker, Eugene
通讯作者：
Kolker, Eugene
影响因子：
4.4
作者：
Craig, R;Cortens, JP;Beavis, RC
通讯作者：
Beavis, RC
影响因子：
3.3
作者：
Higdon, R;Kolker, N;Kolker, E
通讯作者：
Kolker, E