Patients With Lung Cancer Have High Susceptibility of COVID-19: A Retrospective Study in Wuhan, China.
Patients With Lung Cancer Have High Susceptibility of COVID-19: A Retrospective Study in Wuhan, China.
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DOI：
10.1177/1073274820960467
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发表时间：
2020-01
期刊：
影响因子：
--
通讯作者：
Cai H
中科院分区：
文献类型：
--
作者：
Dai MY;Chen Z;Leng Y;Wu M;Liu Y;Zhou F;Ming C;Shao N;Liu M;Cai H
肺癌患者因潜在恶性肿瘤而被认为是COVID-19感染的高风险患者。在我们的研究中，在中国武汉的6家医院共确定了31名患有预先诊断的肺癌的COVID-19患者和186名年龄和性别匹配的非癌症COVID-19患者。多因素分析显示肺癌组IL-6水平明显高于正常对照组。在相同观察时间内，COVID-19肺癌患者的10、20和53天限制平均生存时间早于非癌症COVID-19患者（均P值< 0.05）。我们的研究结果表明，在COVID-19患者中，预先诊断的肺癌与较高的发病率和死亡率相关。
Patients with lung cancer are presumed to be at high risk from COVID-19 infection due to underlying malignancy. A total of 31 COVID-19 patients with pre-diagnosed lung cancer and 186 age and sex matched COVID-19 patients without cancer in 6 hospitals in Wuhan, China were identified in our study. There was a significantly higher level of IL-6 in lung cancer group showed by multifactorial analysis. The restricted mean survival time in 10, 20, and 53 days in COVID-19 patients with lung cancer were ealier than non-cancer COVID-19 patients in the same observation time (all P values < 0.05). Our results indicated that pre-diagnosed lung cancer was associated with higher morbidity and mortality in COVID-19 patients.
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影响因子：
82.9
作者：
Robilotti EV;Babady NE;Mead PA;Rolling T;Perez-Johnston R;Bernardes M;Bogler Y;Caldararo M;Figueroa CJ;Glickman MS;Joanow A;Kaltsas A;Lee YJ;Lucca A;Mariano A;Morjaria S;Nawar T;Papanicolaou GA;Predmore J;Redelman-Sidi G;Schmidt E;Seo SK;Sepkowitz K;Shah MK;Wolchok JD;Hohl TM;Taur Y;Kamboj M
通讯作者：
Kamboj M
DOI：
10.15557/pimr.2020.0003
发表时间：
2020-01-01
影响因子：
3.6
作者：
通讯作者：
--
影响因子：
168.9
作者：
Mack, Michael J.;Leon, Martin B.;Svensson, Lars G.
通讯作者：
Svensson, Lars G.
影响因子：
28.2
作者：
Dai, Mengyuan;Liu, Dianbo;Cai, Hongbing
通讯作者：
Cai, Hongbing
影响因子：
39.2
作者：
Uno H;Wittes J;Fu H;Solomon SD;Claggett B;Tian L;Cai T;Pfeffer MA;Evans SR;Wei LJ
通讯作者：
Wei LJ