Cognitive and physical function in chronic kidney disease.
Cognitive and physical function in chronic kidney disease.
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DOI：
10.1097/01.mnh.0000444821.87873.7b
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发表时间：
2014-05
影响因子：
3.2
通讯作者：
Seliger SL
中科院分区：
文献类型：
--
作者：
Weiner DE;Seliger SL
慢性肾病 (CKD) 患者的认知功能和身体功能通常都会受损，从而对生活质量和整体健康产生重要影响。这篇综述总结了 CKD 认知和身体损害的负担，重点关注最近的研究，这些研究强调了这些共同的共病病症之间可能存在统一的微血管病因。最近发表了多项小型研究，评估了 CKD 患者的认知和身体功能。这些研究总体表明，慢性肾病患者的合并症负担很高，包括微血管疾病，可能导致认知障碍。此外，研究表明，慢性肾病患者的身体机能比预期的要差得多，体力活动减少与更差的结果相关，虚弱很常见，并与死亡风险增加相关，结构化的锻炼计划对身体表现指标的短期影响虽小但明显。认知功能和身体机能受损是影响 CKD 患者生活的重要因素。为了更好地治疗 CKD 患者的这种重要合并症，需要进一步的研究。
Both cognitive and physical function are commonly impaired in individuals with chronic kidney disease (CKD), resulting in important impacts on quality of life and overall health. This review summarizes the burden of cognitive and physical impairment in CKD, focusing on recent research that highlights a possible unifying microvascular etiology among these shared comorbid conditions Multiple small studies have been published recently evaluating cognitive and physical functioning in people with CKD. These studies overall demonstrate a high burden of comorbid conditions in people with CKD, including microvascular disease, that may result in cognitive impairment. Additionally, studies demonstrate that physical function is substantially worse than expected in individuals with CKD, that decreased physical activity is associated with worse outcomes, that frailty is very common and associated with an increased risk of death, and that structured exercise programs have small but tangible short term effects of markers of physical performance. Impaired cognitive function and physical performance are important factors impacting the lives of people with CKD. Further research is necessary to better treat this important comorbid conditions in people with CKD.
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DOI：
10.1053/j.ajkd.2012.08.035
发表时间：
2013-02
期刊：
American journal of kidney diseases : the official journal of the National Kidney Foundation
影响因子：
--
作者：
Drew DA;Bhadelia R;Tighiouart H;Novak V;Scott TM;Lou KV;Shaffi K;Weiner DE;Sarnak MJ
通讯作者：
Sarnak MJ
DOI：
10.2215/cjn.11321112
发表时间：
2013-11-07
影响因子：
9.8
作者：
Barzilay, Joshua I.;Lovato, James F.;Launer, Lenore J.
通讯作者：
Launer, Lenore J.
影响因子：
4.2
作者：
Reese, Peter P.;Cappola, Anne R.;Leonard, Mary B.
通讯作者：
Leonard, Mary B.
影响因子：
13.2
作者：
Bowling, C. Barrett;Muntner, Paul;Allman, Richard M.
通讯作者：
Allman, Richard M.
用加速度计测量维持性血液透析患者的习惯性体力活动量与存活率
DOI：
10.2215/cjn.03660412
发表时间：
2012-12-01
影响因子：
9.8
作者：
Matsuzawa, Ryota;Matsunaga, Atsuhiko;Takahira, Naonobu
通讯作者：
Takahira, Naonobu