Omega-3: a link between global climate change and human health.
Omega-3: a link between global climate change and human health.
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DOI：
10.1016/j.biotechadv.2011.02.003
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发表时间：
2011-07
影响因子：
16
通讯作者：
Kang, Jing X.
中科院分区：
文献类型：
--
作者：
Kang, Jing X.
关键词：
近年来，全球气候变化已被证明对许多生物和环境因素，包括海洋生态系统的生物和环境因素产生不利影响。特别是，全球气候变化与大气中二氧化碳、紫外线照射和海洋温度的增加有关，导致海洋浮游植物生长减少，ω-3多不饱和脂肪酸（PUFA）的合成减少。海洋浮游植物是ω-3多不饱和脂肪酸的主要生产者，ω-3多不饱和脂肪酸是人类正常生长和发育的必需营养素，对人类健康有许多有益的影响。因此，气候变化对海洋的这些不利影响可能会减少我们饮食中omega-3 PUFA的可用性，加剧现代omega-3 PUFA的缺乏和组织omega-6/omega-3 PUFA比例的不平衡，这与心血管疾病，癌症，糖尿病和神经退行性疾病的风险增加有关。本文通过将omega-3 PUFA的可用性确定为潜在的重要联系，为全球气候变化与人类健康之间的关系提供了新的见解，并提出了一种生物技术策略，以解决全球气候变化导致的人类饮食中omega-3 PUFA的潜在短缺。
In recent years, global climate change has been shown to detrimentally affect many biological and environmental factors, including those of marine ecosystems. In particular, global climate change has been linked to an increase in atmospheric carbon dioxide, UV irradiation, and ocean temperatures, resulting in decreased marine phytoplankton growth and reduced synthesis of omega-3 polyunsaturated fatty acids (PUFAs). Marine phytoplankton are the primary producers of omega-3 PUFAs, which are essential nutrients for normal human growth and development and have many beneficial effects on human health. Thus, these detrimental effects of climate change on the oceans may reduce the availability of omega-3 PUFAs in our diets, exacerbating the modern deficiency of omega-3 PUFAs and imbalance of the tissue omega-6/omega-3 PUFA ratio, which have been associated with an increased risk for cardiovascular disease, cancer, diabetes, and neurodegenerative disease. This article provides new insight into the relationship between global climate change and human health by identifying omega-3 PUFA availability as a potentially important link, and proposes a biotechnological strategy for addressing the potential shortage of omega-3 PUFAs in human diets resulting from global climate change.
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