Organocatalyzed [3+3] Annulations for the Construction of Heterocycles
Organocatalyzed [3+3] Annulations for the Construction of Heterocycles
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有机催化 [3 3] 杂环结构的环化
DOI：
10.1055/s-0039-1690810
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发表时间：
2020-02
期刊：
影响因子：
--
通讯作者：
Huang You
中科院分区：
文献类型：
--
作者：
Zhu Yannan;Huang You
Abstract Six-membered heterocyclic systems are widely distributed in many natural products and pharmaceuticals, and the construction of highly functionalized six-membered heterocyclic compounds is an important topic in modern organic synthesis. Organocatalyzed [3+3] annulations represents an important method for assembling a substantial variety of six-membered cycles that contain one or more heteroatoms. This review describes the development of organocatalyzed [3+3] annulations for the synthesis of six-membered heterocycles, including organocatalysis using secondary amines, tertiary amines, phosphines, chiral phosphoric acids and N-heterocyclic carbenes. 1 Introduction 2 Secondary Amine Catalyzed [3+3] Annulations 2.1 Synthesis of Nitrogen Heterocycles 2.2 Synthesis of Oxygen Heterocycles 2.3 Synthesis of Sulfur Heterocycles 3 Tertiary Amine Catalyzed [3+3] Annulations 3.1 Catalysis through Multiple Hydrogen-Bonding Interactions 3.2 Catalysis of Tertiary Amines as Lewis Bases 4 Phosphine-Catalyzed [3+3] Annulations 4.1 Synthesis of Nitrogen Heterocycles 4.2 Synthesis of Oxygen Heterocycles 4.3 Synthesis of Heterocycles Containing Two or More Heteroatoms 5 Chiral Phosphoric Acid Catalyzed [3+3] Annulations 5.1 Synthesis of Nitrogen Heterocycles 5.2 Synthesis of Heterocycles Containing Two or More Heteroatoms 6 N-Heterocyclic Carbene Catalyzed [3+3] Annulations 6.1 Synthesis of Nitrogen Heterocycles 6.2 Synthesis of Oxygen Heterocycles 6.3 Synthesis of Heterocycles Containing Two or More Heteroatoms 7 Conclusion and Outlook
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影响因子：
15
作者：
Marigo, M;Schulte, T;Jorgensen, KA
通讯作者：
Jorgensen, KA
通过有机催化对映选择性缩甲醛[3 3]与双亲核双酮硫醚的环加成反应不对称合成手性二氢噻喃
影响因子：
5.2
作者：
Wang Shengzheng;Zhang Yongqiang;Dong Guoqiang;Wu Shanchao;Zhu Shiping;Miao Zhenyuan;Yao Jianzhong;Li Hao;Li Jian;Zhang Wannian;Sheng Chunquan;Wang Wei
通讯作者：
Wang Wei
影响因子：
15
作者：
Okino, T;Hoashi, Y;Takemoto, Y
通讯作者：
Takemoto, Y
影响因子：
5.2
作者：
Chen, Xiang;Qi, Zheng-Hang;Wang, Xing-Wang
通讯作者：
Wang, Xing-Wang
DOI：
10.1016/c2009-0-14704-9
发表时间：
2016
期刊：
--
影响因子：
--
作者：
Marina Schroder
通讯作者：
Marina Schroder