Laboratory Diagnosis for SARS-CoV-2 Infection.

Laboratory Diagnosis for SARS-CoV-2 Infection.
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DOI:
10.1016/j.idc.2022.02.002
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发表时间:
2022-06
影响因子:
4.4
通讯作者:
Turbett, Sarah E.
Turbett, Sarah E.
中科院分区:
医学3区
文献类型:
--
作者:
Christensen, Bianca B.;Azar, Marwan M.;Turbett, Sarah E.

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SARS-CoV-2感染的最佳诊断试验应根据患者的临床症状和与症状出现有关的表现来选择。分子检测,通常是逆转录酶聚合酶链式反应,在急性感染期间提供最高的敏感性和特异性,而当结果需要快速扭转或分子检测不可用时,抗原检测也可用于急性诊断。血清学检测通常用于确定先前或晚期感染新冠肺炎的个体。
The optimal diagnostic test for SARS-CoV-2 infection should be selected based on a patient’s clinical syndrome and presentation in relation to symptom onset. Molecular testing, most often reverse-transcriptase polymerase chain reaction, offers the highest sensitivity and specificity during acute infection, whereas antigen testing can also be useful for acute diagnosis when rapid turnaround of results is necessary or if molecular testing is unavailable. Serologic testing is often reserved for identifying individuals with prior or late COVID-19 infection.
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