Pseudomonas aeruginosa Quorum Sensing.
Pseudomonas aeruginosa Quorum Sensing.
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DOI:
10.1007/978-3-031-08491-1_4
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发表时间:
2022
影响因子:
--
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中科院分区:
文献类型:
--
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Pseudomonas aeruginosa, like many bacteria, uses chemical signals to communicate between cells in a process called quorum sensing (QS). QS allows groups of bacteria to sense population density and, in response to changing cell densities, to coordinate behaviors. The P. aeruginosa QS system consists of two complete circuits that involve acyl-homoserine lactone signals and a third system that uses quinolone signals. Together, these three QS circuits regulate the expression of hundreds of genes, many of which code for virulence factors. P. aeruginosa has become a model for studying the molecular biology of QS and the ecology and evolution of group behaviors in bacteria. In this chapter, we recount the history of discovery of QS systems in P. aeruginosa, discuss how QS relates to virulence and the ecology of this bacterium, and explore strategies to inhibit QS. Finally, we discuss future directions for research in P. aeruginosa QS.
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影响因子:
3.2
作者:
BRINT, JM;OHMAN, DE
通讯作者:
OHMAN, DE
影响因子:
5.2
作者:
Castañeda-Tamez P;Ramírez-Peris J;Pérez-Velázquez J;Kuttler C;Jalalimanesh A;Saucedo-Mora MÁ;Jiménez-Cortés JG;Maeda T;González Y;Tomás M;Wood TK;García-Contreras R
通讯作者:
García-Contreras R
影响因子:
4.4
作者:
Borlee, Bradley R.;Geske, Grant D.;Handelsman, Jo
通讯作者:
Handelsman, Jo
影响因子:
9.4
作者:
Dénervaud, V;TuQuoc, P;van Delden, C
通讯作者:
van Delden, C
DOI:
10.1073/pnas.1819801116
发表时间:
2019-04-02
影响因子:
11.1
作者:
Chen, Ruiyi;Deziel, Eric;Greenberg, E. Peter
通讯作者:
Greenberg, E. Peter