The role of cutaneous dendritic cells in the immunopathogenesis of atopic dermatitis
The role of cutaneous dendritic cells in the immunopathogenesis of atopic dermatitis
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皮肤树突状细胞在特应性皮炎免疫发病机制中的作用
DOI：
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发表时间：
2001
影响因子：
10.3
通讯作者：
J. Harper
中科院分区：
文献类型：
--
作者：
C. Banfield;R. Callard;J. Harper
We review the immunology of atopic dermatitis (AD) and focus attention on the role of cutaneous dendritic cells. AD is a complex immune‐mediated skin disorder characterized by the recruitment of both CD4+ and CD8+ T cells into the skin. T‐helper (Th) 2‐type cytokines are dominant in acute AD skin, while both Th1‐ and Th2‐type cytokines are present in chronic AD. Cutaneous dendritic cells, which are present in increased numbers within AD skin, are believed to play a key part in the activation of T cells in the skin. They may also help to determine the pattern of cytokines produced by activated effector T cells.
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影响因子：
6.5
作者：
Strickland, I;Hauk, PJ;Leung, DYM
通讯作者：
Leung, DYM
影响因子：
14.2
作者：
Hamid, Q;Naseer, T;Leung, DYM
通讯作者：
Leung, DYM
影响因子：
15.9
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BRATTON, DL;HAMID, Q;LEUNG, DYM
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LEUNG, DYM
影响因子：
56.9
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Randolph, GJ;Beaulieu, S;Muller, WA
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Muller, WA
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14.2
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JUJO, K;RENZ, H;LEUNG, DYM
通讯作者：
LEUNG, DYM