Functional specializations of primary auditory afferents on the Mauthner cells: interactions between membrane and synaptic properties.
Functional specializations of primary auditory afferents on the Mauthner cells: interactions between membrane and synaptic properties.
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DOI：
10.1016/j.jphysparis.2009.11.017
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发表时间：
2010-05
影响因子：
--
通讯作者：
Pereda, Alberto E.
中科院分区：
文献类型：
--
作者：
Curti, Sebastian;Pereda, Alberto E.
关键词：
初级听觉传入通常被认为是被动的，时间保持的，沟通的线路。与这种观点相反，硬骨鱼Mauthner细胞的一类特殊听觉传入，一种组织甩尾逃避反应的命令神经元，经历了对高频细胞活动的混合（电和化学）突触的增强。这种特性可能代表了输入敏化的机制，因为这些神经元为Mauthner细胞提供了启动逃避反应的基本信息。我们在这里回顾这些可识别的听觉传入的解剖和生理专业化。特别是，我们讨论了它们的膜和突触特性如何协同作用，以更有效地激活Mauthner细胞。这些神经元的显著功能特化表明，初级听觉传入对听觉处理的贡献可能比人们普遍认为的要复杂得多。
Primary auditory afferents are usually perceived as passive, timing-preserving, lines of communication. Contrasting this view, a special class of auditory afferents to teleost Mauthner cells, a command neuron that organizes tail-flip escape responses, undergoes potentiation of their mixed (electrical and chemical) synapses in response to high frequency cellular activity. This property is likely to represent a mechanism of input sensitization as these neurons provide the Mauthner cell with essential information for the initiation of an escape response. We review here the anatomical and physiological specializations of these identifiable auditory afferents. In particular, we discuss how their membrane and synaptic properties act in concert to more efficaciously activate the Mauthner cells. The striking functional specializations of these neurons suggest that primary auditory afferents might be capable of more sophisticated contributions to auditory processing than has been generally recognized.
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影响因子：
2.5
作者：
Davis, RL
通讯作者：
Davis, RL
DOI：
10.1098/rspb.1985.0037
发表时间：
1985-01-01
期刊：
PROCEEDINGS OF THE ROYAL SOCIETY SERIES B-BIOLOGICAL SCIENCES
影响因子：
--
作者：
BOWE, CM;KOCSIS, JD;WAXMAN, SG
通讯作者：
WAXMAN, SG
影响因子：
3.8
作者：
FUKAMI, Y;FURUKAWA, T;ASADA, Y
通讯作者：
ASADA, Y
影响因子：
56.9
作者：
FURSHPAN, EJ
通讯作者：
FURSHPAN, EJ
影响因子：
16.2
作者：
Cachope, Roger;Mackie, Ken;Pereda, Alberto E.
通讯作者：
Pereda, Alberto E.