Peripheral mechanisms in appetite regulation.
Peripheral mechanisms in appetite regulation.
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DOI:
10.1053/j.gastro.2014.09.016
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发表时间:
2015-05
期刊:
影响因子:
29.4
通讯作者:
Camilleri M
中科院分区:
文献类型:
--
作者:
Camilleri M
Peripheral mechanisms in appetite regulation include the motor functions of the stomach, such as the rate of emptying and accommodation, which convey symptoms of satiation to the brain. The rich repertoire of peripherally released peptides and hormones provides feedback from the arrival of nutrients in different regions of the gut from where they are released to exert effects on satiation, or regulate metabolism through their incretin effects. Ultimately, these peripheral factors provide input to the highly organized hypothalamic circuitry and vagal complex of nuclei to determine cessation of energy intake during meal ingestion, and the return of appetite and hunger after fasting. Understanding these mechanisms is key to the physiological control of feeding and the derangements that occur in obesity and their restoration with treatment (as demonstrated by the effects of bariatric surgery).
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DOI:
10.1136/bmj.g3961
发表时间:
2014-08-27
期刊:
BMJ (Clinical research ed.)
影响因子:
--
作者:
Arterburn DE;Courcoulas AP
通讯作者:
Courcoulas AP
影响因子:
2.9
作者:
Beglinger, C;Degen, L
通讯作者:
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影响因子:
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作者:
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通讯作者:
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影响因子:
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作者:
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通讯作者:
Anvari, M.
影响因子:
2.9
作者:
Banks, William A.
通讯作者:
Banks, William A.