First Detection of SARS-CoV-2 B.1.1.7 Variant of Concern in an Asymptomatic Dog in Spain.

First Detection of SARS-CoV-2 B.1.1.7 Variant of Concern in an Asymptomatic Dog in Spain.
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DOI:
10.3390/v13071379
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发表时间:
2021-07-15
期刊:
Viruses
影响因子:
--
通讯作者:
Sánchez-Vizcaíno JM
Sánchez-Vizcaíno JM
中科院分区:
其他
文献类型:
--
作者:
Barroso-Arévalo S;Rivera B;Domínguez L;Sánchez-Vizcaíno JM

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在过去的一年里,宠物自然感染SARS-CoV-2的情况得到了广泛的记录。虽然大多数报告表明,狗对感染的易感性很低,但对病毒的致病性和传播性知之甚少,如该物种中的B.1.1.7。在这里,作为一项关于西班牙宠物中SARS-CoV-2流行率的大规模研究的一部分,我们在一只狗中检测到了B.1.1.7变异体(VOC),该狗的主人感染了SARS-CoV-2。该动物未出现任何症状,但鼻拭子和直肠拭子中的病毒载量较高。此外,从两种拭子中均可能分离出病毒,表明犬正在散发传染性病毒。第一次采样后23天发生血清转化。本研究记录了西班牙首次在犬中检测到B.1.1.7 VOC,并强调了对受感染动物进行主动监测和基因组研究的重要性。
Natural SARS-CoV-2 infection in pets has been widely documented during the last year. Although the majority of reports suggested that dogs’ susceptibility to the infection is low, little is known about viral pathogenicity and transmissibility in the case of variants of concern, such as B.1.1.7 in this species. Here, as part of a large-scale study on SARS-CoV-2 prevalence in pets in Spain, we have detected the B.1.1.7 variant of concern (VOC) in a dog whose owners were infected with SARS-CoV-2. The animal did not present any symptoms, but viral loads were high in the nasal and rectal swabs. In addition, viral isolation was possible from both swabs, demonstrating that the dog was shedding infectious virus. Seroconversion occurred 23 days after the first sampling. This study documents the first detection of B.1.1.7 VOC in a dog in Spain and emphasizes the importance of performing active surveillance and genomic investigation on infected animals.
SARS-COV-2血统的估计可传播和影响B.1.1.7在英国。
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