Target volume and motion position evaluation of four-dimensional cone-beam CT: comparison with 4D-CT using dynamic thorax phantom
Target volume and motion position evaluation of four-dimensional cone-beam CT: comparison with 4D-CT using dynamic thorax phantom
复制标题
四维锥束CT靶区体积和运动位置评估：与动态胸部体模4D-CT的比较
DOI：
10.1088/2057-1976/ab1054
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发表时间：
2019
影响因子：
1.4
通讯作者：
Ryo Toya
中科院分区：
文献类型：
--
作者：
Yasuhiro Doi;Yoshinobu Shimohigashi;Yohei Yotsuji;Masato Maruyama;Yudai Kai;Ryo Toya
目的：通过与4D- ct的对比，评价4D锥束计算机断层扫描（CBCT）在动态胸廓成像中的靶体积（TV）清晰度和运动定位精度。方法采用动态胸廓成像技术获取呼吸运动的四维图像。目标直径为20mm，运动周期分别为3,4,6 s，运动模式分别为sin和cos6曲线对应的1D和3D模式。通过对所有4D数据集的阈值分割，对所有10个相位图像进行TV清晰度轮廓化。电视联盟被定义为内部目标卷（ITV）。将TV和ITV与理论TV R和ITV R进行比较。为了评估运动位置，测量TV质心位置并计算这些测量位置相对于幻影设置位置的均方根误差（rmse）。此外，还对肺肿瘤患者的呼吸方式进行了评估。结果4D-CT的TV和ITV在cos 6运动模式下的最大差异分别为0.66 cm 3和- 14.03%，周期为3 s。相比之下，4D-CBCT的TV和ITV在所有运动模式和时期的最大平均差异分别为0.43 cm 3和- 6.48%。大多数运动模式的4D-CT和4D-CBCT的均方根误差在2.5 mm以内。对于患者呼吸模式，4D-CT和4D-CBCT在TV、ITV和体位上的平均差异分别为0.18 cm 3、0.23 cm 3和1.1 mm。结论虽然4D-CT和4D-CBCT在图像采集和体素大小上存在差异，但4D-CBCT的电视和运动定位精度与4D-CT一致。
PurposeThis study evaluated the target volume (TV) definition and motion position accuracies of 4D cone-beam computed tomography (CBCT) through comparison with 4D-CT, using a dynamic thorax phantom.MethodsA dynamic thorax phantom was used to acquire 4D images with respiration motion. Targets with 20-mm diameters, motion periods of 3, 4, and 6 s, and 1D and 3D motion patterns corresponding to sin and cos 6 curves were used. The TV definition was contoured on all 10 phase images via threshold segmentation on all 4D datasets. The TV union was defined as the internal target volume (ITV). The TV and ITV were compared to the theoretical TV R and ITV R. For motion position evaluation, the TV centroid positions were measured and the root mean square errors (RMSEs) of these measured positions calculated relative to the phantom setup positions. In addition, the breathing patterns of patients with lung tumor were evaluated.ResultsThe maximum differences in TV and ITV for 4D-CT were 0.66 cm 3 and− 14.03% for a cos 6 motion pattern with a 3-s period, respectively. In contrast, the maximum average differences in TV and ITV for 4D-CBCT were 0.43 cm 3 and− 6.48%, respectively, for all motion patterns and periods. The 4D-CT and 4D-CBCT RMSEs were within 2.5 mm for most motion patterns. For patient breathing patterns, the average differences in TV, ITV, and positions between 4D-CT and 4D-CBCT were 0.18 cm 3, 0.23 cm 3, and 1.1 mm, respectively.ConclusionsAlthough 4D-CT and 4D-CBCT have differences in image acquisition and voxel size, the TV and motion position accuracies for 4D-CBCT are consistent with those of 4D-CT.
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影响因子：
2.6
作者：
Yoganathan, S. A.;Maria, K. J.;Kumar, Shaleen
通讯作者：
Kumar, Shaleen
动态胸部体模四维锥形束计算机断层扫描采集参数和目标运动轨迹精度优化
影响因子：
1.6
作者：
Y. Shimohigashi;F. Araki;M. Maruyama;Y. Nakaguchi;K. Nakato;Nozomu Nagasue;Yudai Kai
通讯作者：
Yudai Kai
影响因子：
3.5
作者：
Shirato, H;Seppenwoolde, Y;Shimizu, S
通讯作者：
Shimizu, S
DOI：
10.1016/j.ijrobp.2005.05.034
发表时间：
2005-12-01
影响因子：
7
作者：
Nagata, Y;Takayama, K;Hiraoka, M
通讯作者：
Hiraoka, M
4D图像质量对目标定义精度的影响
影响因子：
--
作者：
T. Nielsen;C. Hansen;J. Westberg;O. Hansen;C. Brink
通讯作者：
C. Brink