Taste cells with synapses in rat circumvallate papillae display SNAP‐25‐like immunoreactivity
Taste cells with synapses in rat circumvallate papillae display SNAP‐25‐like immunoreactivity
复制标题
大鼠外周乳头中带有突触的味觉细胞表现出类似 SNAP-25 的免疫反应性
DOI：
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复制
发表时间：
2000
期刊：
影响因子：
--
通讯作者：
J. C. Kinnamon
中科院分区：
文献类型：
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作者：
Ruibiao Yang;H. Crowley;M. Rock;J. C. Kinnamon
Snap-25是一种25 kDa的蛋白质，被认为参与了与神经递质释放相关的膜融合和胞吐过程。在本研究中，我们提出的证据表明，SNAP-25样免疫反应可作为大鼠环状乳头内有突触的味觉细胞的标记。Snap-25免疫反应存在于大多数宝石内神经突起和一小部分味觉细胞中。强烈的免疫反应与位于味蕾底部下方的神经丛有关。在87个与神经突起有突触的味觉细胞中，有80个突触前味觉细胞呈SNAP-25免疫反应阳性。SNAP-25免疫反应与具有突触的味觉细胞的联系表明，这些细胞可能是味觉受体细胞。由于这种SNAP-25抗体可以用突触标记味觉细胞，它也可能成为未来研究味蕾结构与功能相关的有用工具。J.Comp.神经。424：205-215,2000。©2000 Wiley-Liss Inc.
SNAP‐25 is a 25 kDa protein believed to be involved in the processes of membrane fusion and exocytosis associated with neurotransmitter release. In the present study we present evidence that SNAP‐25‐like immunoreactivity can be used as a marker for taste cells with synapses in rat circumvallate papillae. SNAP‐25 immunoreactivity is present in most intragemmal nerve processes and a small subset of taste cells. Intense immunoreactivity is associated with the nerve plexus located below the base of the taste bud. Of a total of 87 taste cells with synapses onto nerve processes, 80 of the presynaptic taste cells had SNAP‐25 immunoreactivity. The association of SNAP‐25 immunoreactivity with taste cells possessing synapses suggests that these cells may be gustatory receptor cells. Because this SNAP‐25 antibody can label taste cells with synapses, it may also serve as a useful tool for future studies correlating structure with function in the taste bud. J. Comp. Neurol. 424:205–215, 2000. © 2000 Wiley‐Liss, Inc.
脊椎动物味觉受体的细胞生物学。
影响因子：
13.9
作者：
Roper,SD
通讯作者：
Roper,SD
DOI：
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发表时间：
1995-07
期刊：
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影响因子：
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作者：
A. Spielman;J. Brand
通讯作者：
A. Spielman;J. Brand
DOI：
10.1073/pnas.92.5.1510
发表时间：
1995-02-28
影响因子：
11.1
作者：
BARK, IC;HAHN, KM;WILSON, MC
通讯作者：
WILSON, MC