Associations of the COVID-19 pandemic with quality of life: A cross-sectional study of older-age people with and without HIV in rural Uganda.
Associations of the COVID-19 pandemic with quality of life: A cross-sectional study of older-age people with and without HIV in rural Uganda.
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DOI：
10.7189/jogh.13.06003
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发表时间：
2023-01-20
影响因子：
7.2
通讯作者：
Siedner MJ
中科院分区：
文献类型：
--
作者：
Olivieri-Mui B;Hoeppner SS;Tong Y;Kohrt E;Quach LT;Saylor D;Seeley J;Tsai AC;Reynolds Z;Okello S;Asiimwe S;Flavia A;Sentongo R;Tindimwebwa E;Meyer AC;Nakasujja N;Paul R;Ritchie C;Greene M;Siedner MJ
与新冠肺炎相关的封锁和其他公共卫生措施可能对乌干达农村地区携带和不携带人类免疫缺陷病毒的老年人的生活质量产生了不同的影响。乌干达农村艾滋病毒携带者的生活质量和老龄化研究从2020年10月到2021年10月招募了49岁以上的艾滋病毒携带者和非艾滋病毒携带者。我们收集了与新冠肺炎相关的压力源(行为变化、担忧、医疗保健、收入和食物方面的干扰)以及参与者的生活质量的数据。我们使用线性回归来估计新冠肺炎相关压力源和生活质量之间的关联，调整了人口统计学特征、心理和身体健康，以及乌干达第二次新冠肺炎浪潮期间封锁前和封锁后的时间。艾滋病病毒和新冠肺炎相关应激源之间的交互作用评估了效果修正。我们分析了562名参与者的完整数据。平均年龄为58岁(标准差(SD) = 7)；265名(47%)为女性，386名(69%)已婚，279名(50%)携带艾滋病毒，400名(71%)为农民。发生≥5新冠肺炎相关行为改变的患者总体生活质量(估计线性回归系数(B) = - 4.77；95%可信区间 = -6.61，-2.94)和健康相关生活质量(b = -4.60；95%CI = -8.69，-0.51)较差。在新冠肺炎大流行开始后获得足够的食物(b = 3.10，95%CI = 1.54，4.66)和在第二次封锁开始后接受采访(b = 2.79，95%CI = 1.30，4.28)与较好的总体生活质量相关。感染艾滋病毒与较好的健康相关生活质量相关(b = 5.67，95%CI = 2.91，8.42)。艾滋病毒与新冠肺炎相关的压力源与一般生活质量之间没有关联，也没有改变这种关联。在艾滋病毒流行、资源匮乏的新冠肺炎大流行背景下，老年乌干达人的生活质量下降，出现了多个与新冠肺炎相关的行为变化。尽管如此，第二次新冠肺炎浪潮期间的良好生活质量可能表明，老年乌干达人具有韧性。
COVID-19-related lockdowns and other public health measures may have differentially affected the quality of life (QOL) of older people with and without human immunodeficiency virus (HIV) in rural Uganda. The Quality of Life and Aging with HIV in Rural Uganda study enrolled people with and without HIV aged over 49 from October 2020 to October 2021. We collected data on COVID-19-related stressors (behavior changes, concerns, interruptions in health care, income, and food) and the participants’ QOL. We used linear regression to estimate the associations between COVID-19-related stressors and QOL, adjusting for demographic characteristics, mental and physical health, and time before vs after the lockdown during the second COVID-19 wave in Uganda. Interaction between HIV and COVID-19-related stressors evaluated effect modification. We analyzed complete data from 562 participants. Mean age was 58 (standard deviation (SD) = 7); 265 (47%) participants were female, 386 (69%) were married, 279 (50%) had HIV, and 400 (71%) were farmers. Those making ≥5 COVID-19-related behavior changes compared to those making ≤2 had worse general QOL (estimated linear regression coefficient (b) = - 4.77; 95% confidence interval (CI) = -6.61, -2.94) and health-related QOL (b = -4.60; 95% CI = -8.69, -0.51). Having access to sufficient food after the start of the COVID-19 pandemic (b = 3.10, 95% CI = 1.54, 4.66) and being interviewed after the start of the second lockdown (b = 2.79, 95% CI = 1.30, 4.28) were associated with better general QOL. Having HIV was associated with better health-related QOL (b = 5.67, 95% CI = 2.91,8.42). HIV was not associated with, nor did it modify the association of COVID-19-related stressors with general QOL. In the context of the COVID-19 pandemic in an HIV-endemic, low-resource setting, there was reduced QOL among older Ugandans making multiple COVID-19 related behavioral changes. Nonetheless, good QOL during the second COVID-19 wave may suggest resilience among older Ugandans.
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影响因子：
8.5
作者：
Harling G;Gómez-Olivé FX;Tlouyamma J;Mutevedzi T;Kabudula CW;Mahlako R;Singh U;Ohene-Kwofie D;Buckland R;Ndagurwa P;Gareta D;Gunda R;Mngomezulu T;Nxumalo S;Wong EB;Kahn K;Siedner MJ;Maimela E;Tollman S;Collinson M;Herbst K
通讯作者：
Herbst K
影响因子：
2.6
作者：
Mugisha, Joseph O.;Schatz, Enid J.;Seeley, Janet
通讯作者：
Seeley, Janet
DOI：
10.1073/pnas.1219686110
发表时间：
2013-04-09
影响因子：
11.1
作者：
Steptoe, Andrew;Shankar, Aparna;Wardle, Jane
通讯作者：
Wardle, Jane
影响因子：
3.7
作者：
Dessie ZG;Zewotir T
通讯作者：
Zewotir T
影响因子：
2.8
作者：
Siedner MJ
通讯作者：
Siedner MJ