In vivo imaging of corneal inflammation: new tools for clinical practice and research.

In vivo imaging of corneal inflammation: new tools for clinical practice and research.
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DOI:
10.3109/08820538.2010.518542
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发表时间:
2010-09
影响因子:
1.7
通讯作者:
Hamrah P
Hamrah P
中科院分区:
医学4区
文献类型:
--
作者:
Mantopoulos D;Cruzat A;Hamrah P

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Infectious and inflammatory corneal diseases are a major cause of blindness. To date, assessment of corneal inflammation, has only been possible by slit-lamp biomicroscopy. The purpose of this study is to review the current state of imaging technologies enabling in vivo imaging of inflammation in the cornea. Literature review of peer-reviewed articles on in vivo imaging modalities. Current means of diagnosis and treatment follow-up for immune and infectious keratitis are limited to slit-lamp biomicroscopy. Several modalities are currently emerging, allowing for in vivo imaging of corneal inflammation, including in vivo confocal microscopy, anterior segment optical coherence tomography, and intravital multiphoton microscopy. Several in vivo imaging technologies are currently evolving, allowing for objective assessment of corneal inflammation and treatment response.
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