The effects of high-intensity interval training and moderate-intensity continuous training on visceral fat and carotid hemodynamics parameters in obese adults.
The effects of high-intensity interval training and moderate-intensity continuous training on visceral fat and carotid hemodynamics parameters in obese adults.
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高强度间歇训练和中等强度持续训练对肥胖成人内脏脂肪和颈动脉血流动力学参数的影响
DOI：
10.1016/j.jesf.2022.09.001
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发表时间：
2022-10
影响因子：
2.8
通讯作者：
Tang, Donghui
中科院分区：
文献类型：
--
作者：
Shi, Wenxia;Chen, Jiangang;He, Yufeng;Su, Pei;Wang, Mengyue;Li, Xulong;Tang, Donghui
关键词：
本研究旨在探讨高强度间歇训练（HIIT）和中等强度持续训练（MICT）对肥胖成年人内脏脂肪和血流动力学参数的影响。本研究纳入了52只雄性动物，并分为3组：HIIT集团（n = 21，年龄= 20.86 ± 1.62岁，BF（%）= 30.10 ± 5.02），MICT组（n = 22，年龄= 20.76 ± 1.14岁，BF（%）= 30.19 ± 5.76）和对照组（n = 9，年龄= 21.38 ± 1.77岁，BF（%）= 30.40 ± 5.10）。HIIT组和MICT组每周接受3 ~ 4次运动干预，共8周（HIIT组：运动强度80- 95%HRmax，循环; MICT组：运动强度60- 70%HRmax，跑步），对照组（CON组）接受健康教育和指导，不进行运动干预。测定体成分和血脂指标，计算BMI和VAI。采用彩色多普勒超声诊断技术检测介入治疗前后动脉内径及血流速度。根据实验数据，采用MATLAB软件和Womersley理论计算颈总动脉的血流动力学参数，包括壁面切应力、流速、血压、振荡剪切指数、弹性模量、动态阻力、动脉直径、动脉刚度、周向应变和搏动指数。我们发现HIIT组（p < 0.01）和MICT组（p < 0.05）的脂质累积产物（lipid accumulation product，CYP）均显著降低，但CON组无显著变化（p > 0.05）。相反，内脏脂肪指数（VAI）在HIIT和MICT组均降低，CON组升高，但组间差异不显著（p > 0.05）。干预8周后，HIIT和MICT干预后血流速度和壁面切应力均高于对照组（p < 0.01）。HIIT组的动脉直径、振荡剪切指数、动脉硬度和脉动指数显著降低，周向应变显著增加（所有，p < 0.01，p < 0.05），但MICT组没有（p > 0.05）。MICT组的动态阻力显著降低。干预后CON组无差异（均为p > 0.05）。动脉内径与血管内径呈正相关（r = 0.48，p = 0.011），血压（r = 0.46，p = 0.002），流速（r = 0.31，p = 0.04），振荡剪切指数（r = 0.44，p = 0.03）和弹性模量（r = 0.33，p = 0.029），但与周向应变呈负相关（r =-0.36，p = 0.028）。VAI还与动脉直径（r = 0.33，p = 0.03）、弹性模量（r = 0.38，p = 0.009）和动脉硬度（r = 0.39，p = 0.012）呈正相关。此外，VAI与周向应变呈负相关（r =-0.33，p = 0.04）。本研究表明，HIIT和MICT运动8周后，内脏脂肪指数和部分血流动力学参数均得到有效提高。因此，HIIT和MICT在降低脂肪含量和改善血流动力学环境方面具有重要作用。但HIIT在振荡剪切指数、动脉僵硬度、环向应变和搏动指数方面优于MICT，差异有上级。此外，内脏脂肪与颈总动脉部分血流动力学参数有密切的相关性。
The present study aimed to examine the effects of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on visceral fat and hemodynamic parameters in obese adults. Fifty-two males were included in this study and divided into three groups: HIIT group (n = 21, age = 20.86 ± 1.62 years, BF (%) = 30.10 ± 5.02), MICT group (n = 22, age = 20.76 ± 1.14 years, BF (%) = 30.19 ± 5.76), and control group (CON) (n = 9, age = 21.38 ± 1.77 years, BF (%) = 30.40 ± 5.10). The HIIT and MICT groups received the exercise intervention three to four times per week for eight weeks (HIIT: exercise intensity 80–95% HRmax, circuit; MICT: exercise intensity 60–70% HRmax, running), and the control (CON) group received health education and guidance without exercise intervention. The body compositions and serum lipid indexes were tested to calculated LAP and VAI. The color doppler ultrasound diagnostic technology was used to test the artery diameter and blood velocity before and after the intervention. Based on the test data, MATLAB software and Womersley theory were used to calculate the hemodynamic parameters of the common carotid artery, including wall shear stress, flow rate, blood pressure, oscillatory shear index, elasticity modulus, dynamic resistance, artery diameter, arterial stiffness, circumferential strain and pulsatility index. We found that lipid accumulation product (LAP) was significantly decreased in both the HIIT group (p < 0.01) and MICT (p < 0.05) group but not in the CON group (p > 0.05). In contrast, visceral adiposity index (VAI) decreased in both the HIIT and MICT groups and increased in the CON group, although the difference among groups was not significant (p > 0.05). After 8 weeks of intervention, the blood velocity and wall shear stress were greater after HIIT and MICT intervention (p < 0.01). Artery diameter, oscillatory shear index, arterial stiffness, and pulsatility index decreased significantly, and circumferential strain increased significantly in the HIIT group (all, p < 0.01, p < 0.05) but not in the MICT group (p > 0.05). Dynamic resistance was significantly decreased in the MICT group. There was no difference in the CON group after the period of intervention (all, p > 0.05). LAP was positively related to artery diameter (r = 0.48, p = 0.011), blood pressure (r = 0.46, p = 0.002), flow rate (r = 0.31, p = 0.04), oscillatory shear index (r = 0.44, p = 0.03), and elasticity modulus (r = 0.33, p = 0.029) but inversely related to circumferential strain (r = −0.36, p = 0.028). The VAI was also positively associated with artery diameter (r = 0.33, p = 0.03), elasticity modulus (r = 0.38, p = 0.009), and arterial stiffness (r = 0.39, p = 0.012). In addition, the VAI was negatively correlated with the circumferential strain (r = −0.33, p = 0.04). The present study demonstrated that both HIIT and MICT exercises for 8 weeks could effectively enhance visceral fat indices and partial hemodynamic parameters. Therefore, HIIT and MICT exert important effects on reducing fat content and improving hemodynamic environment. But HIIT on oscillatory shear index, arterial stiffness, circumferential strain, and pulsatility index was superior to MICT. In addition, there are close correlations between visceral fat and partial hemodynamic parameters of the common carotid artery.
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