A survey of protocols from 54 infant and toddler neuroimaging research labs.
A survey of protocols from 54 infant and toddler neuroimaging research labs.
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DOI：
10.1016/j.dcn.2022.101060
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发表时间：
2022-04
影响因子：
4.7
通讯作者：
Thomason ME
中科院分区：
文献类型：
--
作者：
Hendrix CL;Thomason ME
婴儿和幼儿MRI能够前所未有地深入了解发育中的大脑。然而，缺乏关于最佳数据收集做法的共识，这减缓了该领域的增长，阻碍了复制工作。本研究的目的是收集大量婴儿/幼儿研究实验室的系统数据，以更好地了解首选做法。调查数据涉及MRI采集策略、扫描成功率、访视准备、扫描方案、家庭住宿、研究设计和关于偶然发现的政策。受访者平均有8年的经验，在生命早期的神经成像和代表超过50个研究实验室。各实验室达成共识的领域包括新生儿的成功率高于年龄较大的婴儿或幼儿，各年龄组的数据丢失率较高，多层听力保护的认可，以及特定年龄的扫描准备和参与者的适应性。研究人员在纵向研究设计和实践中对偶然发现的决定仍然存在分歧。这项研究总结了大量科学家多年来的工作实践，这可能是该领域新手的重要资源。能够参考有关最佳实践的数据有助于未来的协调，数据共享和可重复性，所有这些都推动了发展科学的这一重要前沿。婴儿/幼儿MRI扫描的成功率存在很高的实验室间差异。婴儿/幼儿MRI扫描将受益于独特的机构住宿。大多数实验室至少使用3层听力保护。专家们报告了关于偶然发现的不同建议。
Infant and toddler MRI enables unprecedented insight into the developing brain. However, consensus about optimal data collection practices is lacking, which slows growth of the field and impedes replication efforts. The goal of this study was to collect systematic data across a large number of infant/toddler research laboratories to better understand preferred practices. Survey data addressed MRI acquisition strategies, scan success rates, visit preparations, scanning protocols, accommodations for families, study design, and policies regarding incidental findings. Respondents had on average 8 years’ experience in early life neuroimaging and represented more than fifty research laboratories. Areas of consensus across labs included higher success rates among newborns compared to older infants or toddlers, high rates of data loss across age groups, endorsement of multiple layers of hearing protection, and age-specific scan preparation and participant accommodation. Researchers remain divided on decisions in longitudinal study design and practices regarding incidental findings. This study summarizes practices honed over years of work by a large collection of scientists, which may serve as an important resource for those new to the field. The ability to reference data about best practices facilitates future harmonization, data sharing, and reproducibility, all of which advance this important frontier in developmental science. There is high inter-lab variability in success rates for infant/toddler MRI scans. Infant/toddler MRI scanning would benefit from unique institutional accommodations. At least 3 layers of hearing protection are used by the majority of labs. Experts report heterogeneous recommendations regarding incidental findings.
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影响因子：
15.1
作者：
Carney O;Hughes E;Tusor N;Dimitrova R;Arulkumaran S;Baruteau KP;Collado AE;Cordero-Grande L;Chew A;Falconer S;Allsop JM;Rueckert D;Hajnal J;Edwards AD;Rutherford M
通讯作者：
Rutherford M
DOI：
10.1053/j.nainr.2008.10.010
发表时间：
2008-12-01
期刊：
NEWBORN AND INFANT NURSING REVIEWS
影响因子：
--
作者：
Graven, Stanley N.;Browne, Joy V.
通讯作者：
Browne, Joy V.
DOI：
10.1177/1073858416635986
发表时间：
2017-04
期刊：
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry
影响因子：
--
作者：
Gao W;Lin W;Grewen K;Gilmore JH
通讯作者：
Gilmore JH
影响因子：
2.9
作者：
Grewen K;Salzwedel AP;Gao W
通讯作者：
Gao W
DOI：
10.1016/j.bpsc.2020.11.003
发表时间：
2021-04
期刊：
Biological psychiatry. Cognitive neuroscience and neuroimaging
影响因子：
--
作者：
Hendrix CL;Dilks DD;McKenna BG;Dunlop AL;Corwin EJ;Brennan PA
通讯作者：
Brennan PA