PlantMarkers--a database of predicted molecular markers from plants.

PlantMarkers--a database of predicted molecular markers from plants.
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DOI:
10.1093/nar/gki074
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发表时间:
2005-01-01
影响因子:
14.9
通讯作者:
Mayer K
Mayer K
中科院分区:
生物学2区
文献类型:
--
作者:
Rudd S;Schoof H;Mayer K

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在广泛的基因筛选方法中都需要分子标记,从传统的前向遗传学方法中的基因作图,到QTL鉴定研究,再到基因分型和单倍型研究。随着我们进入后基因组时代,对遗传标记的需求不会减少,即使在拥有完全测序基因组的物种中也是如此。PlantMarkers是一个遗传标记数据库,其中包含一个全面的预测分子标记库。我们采用了现代技术来鉴定可能的单核苷酸多态(SNP)、简单序列重复(SSR)和保守的同源集合标记。通过从50多种植物中筛选可用的OpenSputnik Unigene共识序列,已经采取了一种系统的方法来识别尽可能广泛的假定标记。Http://markers.btk.fi上的网络存在提供了功能,使得用户可以基于许多特定标准来搜索物种特定标记,而不限于在不同品种之间分离的非同义SNP或所测量的多态SSR。向反馈表格提供所有序列条目,以允许包括例如由研究团体验证的标记的地图位置。
Molecular markers are required in a broad spectrum of gene screening approaches, ranging from gene-mapping within traditional ‘forward’-genetics approaches through QTL identification studies to genotyping and haplotyping studies. As we enter the post-genomics era, the need for genetic markers does not diminish, even in the species with fully sequenced genomes. PlantMarkers is a genetic marker database that contains a comprehensive pool of predicted molecular markers. We have adopted contemporary techniques to identify putative single nucleotide polymorphism (SNP), simple sequence repeat (SSR) and conserved orthologue set markers. A systematic approach to identify as broad a range of putative markers has been undertaken by screening the available openSputnik unigene consensus sequences from over 50 plant species. A web presence at http://markers.btk.fi provides functionality so that a user may search for species-specific markers on the basis of many specific criteria not limited to non-synonymous SNPs segregating between different varieties or measured polymorphic SSRs. Feedback forms are provided with all sequence entries to enable inclusion of, for example, map location for markers validated by the research community.
DOI: 10.1093/bioinformatics/btf881
发表时间: 2003-02-12
期刊: BIOINFORMATICS
影响因子: 5.8
作者:
Barker, G;Batley, J;Edwards, D
通讯作者: Edwards, D
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发表时间: 2002-07-01
期刊: PLANT CELL
影响因子: 11.6
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DOI: 10.1093/nar/gkg075
发表时间: 2003-01-01
影响因子: 14.9
作者:
Rudd, S;Mewes, HW;Mayer, KFX
通讯作者: Mayer, KFX