Numerical Simulations of the Motion and Deformation of Three RBCs during Poiseuille Flow through a Constricted Vessel Using IB-LBM.
Numerical Simulations of the Motion and Deformation of Three RBCs during Poiseuille Flow through a Constricted Vessel Using IB-LBM.
复制标题
使用 IB-LBM 数值模拟泊肃叶流通过收缩血管期间三个红细胞的运动和变形
DOI：
10.1155/2018/9425375
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发表时间：
2018
影响因子：
--
通讯作者：
Zheng W
中科院分区：
文献类型：
--
作者：
Wang R;Wei Y;Wu C;Sun L;Zheng W
采用浸没边界格子Boltzmann方法（IB-LBM）研究了三种弹性红细胞（RBC）在Poiffille流中的运动和变形.其目的是确定的收缩程度和雷诺数（Re）的流量上的红细胞的物理特性的影响。结果发现，随着收缩比的降低，红细胞经历了更大的强制变形，因为它们挤压通过收缩区域相比，在微通道的其他部分。还观察到，红细胞需要更长的时间才能挤出较窄的收缩。红细胞随后恢复稳定的形状，并逐渐向收缩区以外的流动中心线迁移。然而，当Re数低于0.40时，观察到患病RBC不能通过收缩比≤1/3的收缩血管。
The immersed boundary-lattice Boltzmann method (IB-LBM) was used to examine the motion and deformation of three elastic red blood cells (RBCs) during Poiseuille flow through constricted microchannels. The objective was to determine the effects of the degree of constriction and the Reynolds (Re) number of the flow on the physical characteristics of the RBCs. It was found that, with decreasing constriction ratio, the RBCs experienced greater forced deformation as they squeezed through the constriction area compared to at other parts of the microchannel. It was also observed that a longer time was required for the RBCs to squeeze through a narrower constriction. The RBCs subsequently regained a stable shape and gradually migrated toward the centerline of the flow beyond the constriction area. However, a sick RBC was observed to be incapable of passing through a constricted vessel with a constriction ratio ≤1/3 for Re numbers below 0.40.
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