Synthesis and surface functionalization of silica nanoparticles for nanomedicine.
Synthesis and surface functionalization of silica nanoparticles for nanomedicine.
复制标题
DOI:
10.1016/j.surfrep.2014.07.001
复制
发表时间:
2014-09
影响因子:
9.8
通讯作者:
Kummel, Andrew C.
中科院分区:
文献类型:
--
作者:
Liberman, Alexander;Mendez, Natalie;Trogler, William C.;Kummel, Andrew C.
There are a wide variety of silica nanoformulations being investigated for biomedical applications. Silica nanoparticles can be produced using a wide variety of synthetic techniques with precise control over their physical and chemical characteristics. Inorganic nanoformulations are often criticized or neglected for their poor tolerance; however, extensive studies into silica nanoparticle biodistributions and toxicology have shown that silica nanoparticles may be well tolerated, and in some case are excreted or are biodegradable. Robust synthetic techniques have allowed silica nanoparticles to be developed for applications such as biomedical imaging contrast agents, ablative therapy sensitizers, and drug delivery vehicles. This review explores the synthetic techniques used to create and modify an assortment of silica nanoformulations, as well as several of the diagnostic and therapeutic applications.
登录
查看更多内容
影响因子:
5.5
作者:
Balamurugan, Sreelatha S.;Soto-Cantu, Erick;Russo, Paul S.
通讯作者:
Russo, Paul S.
影响因子:
14
作者:
Huang, Peng;Bao, Le;Cui, Daxiang
通讯作者:
Cui, Daxiang
影响因子:
--
作者:
Cauda, Valentina;Argyo, Christian;Bein, Thomas
通讯作者:
Bein, Thomas
影响因子:
7.4
作者:
He, Xiaoxiao;Nie, Hailong;Zhang, Pengfei
通讯作者:
Zhang, Pengfei
影响因子:
6.7
作者:
Casciaro, Sergio;Conversano, Francesco;Gigli, Giuseppe
通讯作者:
Gigli, Giuseppe