Sensory information in local field potentials and spikes from visual and auditory cortices: time scales and frequency bands.
Sensory information in local field potentials and spikes from visual and auditory cortices: time scales and frequency bands.
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DOI：
10.1007/s10827-010-0230-y
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发表时间：
2010-12
影响因子：
1.2
通讯作者：
Kayser, Christoph
中科院分区：
文献类型：
--
作者：
Belitski, Andrei;Panzeri, Stefano;Magri, Cesare;Logothetis, Nikos K.;Kayser, Christoph
分析感觉皮层处理或试图解码大脑活动的研究通常依赖于不同电生理信号的组合，例如局部场电位（LFP）和尖峰活动。因此，了解这些信号和感官刺激之间的关系以及这些信号的不同组成部分之间的关系非常有趣。我们在这里提供了一个分析的LFPs和尖峰活动记录从视觉和听觉皮层在刺激与自然刺激。特别是，我们专注于这些信号的不同组成部分的时间尺度上的信息的刺激，这些信号的不同组成部分之间的依赖关系。针对第一个问题，我们发现低频带（<12 Hz）的刺激信息很高，无论它们的能量是以毫秒或秒为单位计算的。相比之下，较高频带（>50 Hz）中的刺激信息是尺度相关的，并且当能量在几百毫秒上平均时更大。事实上，信号可靠性和信息的组合分析表明，即使考虑单个或几个周期，缓慢LFP波动的能量也与刺激密切相关，而快速LFP振荡的能量仅在许多周期上平均时才携带信息。解决第二个问题，我们发现，刺激信息在不同的LFP波段，并在不同的LFP波段和尖峰活动，在很大程度上是独立的，无论时间尺度或感觉系统。总之，这些研究结果表明，不同的LFP频段代表不同时间尺度上的动态自然刺激，并共同提供了一个潜在的丰富的信息源，用于感官处理或解码大脑活动。本文的在线版本（doi：10.1007/s10827-010-0230-y）包含补充材料，可供授权用户使用。
Studies analyzing sensory cortical processing or trying to decode brain activity often rely on a combination of different electrophysiological signals, such as local field potentials (LFPs) and spiking activity. Understanding the relation between these signals and sensory stimuli and between different components of these signals is hence of great interest. We here provide an analysis of LFPs and spiking activity recorded from visual and auditory cortex during stimulation with natural stimuli. In particular, we focus on the time scales on which different components of these signals are informative about the stimulus, and on the dependencies between different components of these signals. Addressing the first question, we find that stimulus information in low frequency bands (<12 Hz) is high, regardless of whether their energy is computed at the scale of milliseconds or seconds. Stimulus information in higher bands (>50 Hz), in contrast, is scale dependent, and is larger when the energy is averaged over several hundreds of milliseconds. Indeed, combined analysis of signal reliability and information revealed that the energy of slow LFP fluctuations is well related to the stimulus even when considering individual or few cycles, while the energy of fast LFP oscillations carries information only when averaged over many cycles. Addressing the second question, we find that stimulus information in different LFP bands, and in different LFP bands and spiking activity, is largely independent regardless of time scale or sensory system. Taken together, these findings suggest that different LFP bands represent dynamic natural stimuli on distinct time scales and together provide a potentially rich source of information for sensory processing or decoding brain activity. The online version of this article (doi:10.1007/s10827-010-0230-y) contains supplementary material, which is available to authorized users.
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影响因子：
2.4
作者：
Magri C;Whittingstall K;Singh V;Logothetis NK;Panzeri S
通讯作者：
Panzeri S
影响因子：
16.2
作者：
Kayser, Christoph;Montemurro, Marcelo A.;Panzeri, Stefano
通讯作者：
Panzeri, Stefano
影响因子：
6
作者：
Kayser, C;Einhäuser, W;König, P
通讯作者：
König, P
影响因子：
5.3
作者：
Liu, Jing;Newsome, William T.
通讯作者：
Newsome, William T.
DOI：
10.1073/pnas.95.26.15706
发表时间：
1998-12-22
影响因子：
11.1
作者：
Hatsopoulos, NG;Ojakangas, CL;Donoghue, JP
通讯作者：
Donoghue, JP