The organization of the leuC, leuD and leuB genes of the extreme thermophile Thermus thermophilus.
The organization of the leuC, leuD and leuB genes of the extreme thermophile Thermus thermophilus.
复制标题
极端嗜热栖热菌的 leuC、leuD 和 leuB 基因的组织。
DOI:
10.1016/s0378-1119(98)00482-x
复制
发表时间:
1998
期刊:
影响因子:
3.5
通讯作者:
T. Oshima
中科院分区:
文献类型:
--
作者:
M. Tamakoshi;A. Yamagishi;T. Oshima
3-Isopropylmalate dehydrogenase is encoded by leuB gene while leuC and leuB genes encode the large and small subunits of isopropylmalate isomerase in leucine biosynthetic pathway, respectively. Organization of the leuB, leuC and leuD genes of an extreme thermophile, Thermus thermophilus, was investigated by sequence analysis. Location of the genes was also tested by complementation analysis of leu deficiency of the thermophile and Escherichia coli. The order was the leuC, leuD, and leuB genes and, in contrast to a previous report, they did not overlap with each other. Sequence analysis of the leuC and leuD genes suggested that cysteine residues for iron–sulfur binding and other amino acid residues involved in isomerase activity, which have been inferred from analysis of a related protein, aconitase, were highly conserved.
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DOI:
10.1099/00221287-139-5-1093
发表时间:
1993
期刊:
Journal of general microbiology
影响因子:
--
作者:
Ding,M;Yelton,DB
通讯作者:
Yelton,DB
影响因子:
3.3
作者:
D. Oppenheim;C. Yanofsky
通讯作者:
D. Oppenheim;C. Yanofsky
影响因子:
5.6
作者:
WESSLER, SR;CALVO, JM
通讯作者:
CALVO, JM
DOI:
--
发表时间:
1991
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Mather,MW;Springer,P;Fee,JA
通讯作者:
Fee,JA