Validity of the Instrumented Push and Release Test to Quantify Postural Responses in Persons With Multiple Sclerosis.

Validity of the Instrumented Push and Release Test to Quantify Postural Responses in Persons With Multiple Sclerosis.
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DOI:
10.1016/j.apmr.2017.01.030
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发表时间:
2017-07
影响因子:
4.3
通讯作者:
Huisinga JM
Huisinga JM
中科院分区:
医学1区
文献类型:
--
作者:
El-Gohary M;Peterson D;Gera G;Horak FB;Huisinga JM

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为了测试可穿戴惯性传感器的有效性,以提供对多发性硬化症患者的推和释放临床测试的姿势步进响应的客观测量。横断面大学医学中心平衡障碍实验室52名PwMS和21名年龄匹配的健康对照步进潜伏期,达到稳定所需的时间和步数,和初始步长由放置在参与者腰椎和脚上的三个惯性测量单元计算。惯性传感器测量值与从实验室系统获得的测量值之间的相关性为中等至强,并且对于所有变量具有统计学显著性:时候释放(r = 0.992),潜伏期(r = 0.655)、稳定时间(r = 0.847)、首次着地时间(r = 0.665)、步数(r = 0.825)和首次步长(r = 0.592)。与健康对照相比,PwMS显示出更长的稳定时间,并且需要更多的步骤来达到稳定。仪器化推放试验(IPUSH)是PwMS姿势反应的有效测量方法,可用作患者护理决策或旨在改善PwMS姿势控制的临床试验的临床结局测量。
To test the validity of wearable inertial sensors to provide objective measures of postural stepping responses to the Push and Release clinical test in people with multiple sclerosis Cross-sectional University medical center balance disorders laboratory 52 PwMS and 21 age-matched healthy controls stepping latency, time and number of steps required to reach stability, and initial step length were calculated from three inertial measurement units placed on participants’ lumbar spine and feet. Correlations between the inertial sensor measures and measures obtained from the laboratory-based systems were moderate to strong and statistically significant for all variables: time to release (r = 0.992), latency (r = 0.655), time to stability (r = 0.847), time of first heel strike (r = 0.665), number of steps (r = 0.825) and first step length (r = 0.592). Compared to healthy controls, PwMS demonstrated a longer time to stability and required a larger number of steps to reach stability. The instrumented Push and Release test (IPUSH) is a valid measure of postural responses in PwMS and could be used as a clinical outcome measures for patient care decisions or for clinical trials aimed at improving postural control in PwMS.
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