Expression of the murine homeo box gene Hox 1.5 during embryogenesis.

Expression of the murine homeo box gene Hox 1.5 during embryogenesis.
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小鼠同源框基因 Hox 1.5 在胚胎发生过程中的表达。

DOI:
10.1016/0012-1606(87)90465-9
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发表时间:
1987
影响因子:
2.7
通讯作者:
Ruddle,FH
Ruddle,FH
中科院分区:
生物学3区
文献类型:
--
作者:
Fainsod,A;Awgulewitsch,A;Ruddle,FH

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研究了小鼠同源盒基因Hox 1.5在胚胎发育过程中的空间表达模式。用单链RNA探针与小鼠胚胎切片进行原位杂交,发现Hox 1.5转录产物在性交后8.5~12.5天的小鼠胚胎中有特定的空间分布。小鼠胚胎发育8.5d的分析。结果表明,该基因以空间受限的方式表达。表达似乎仅限于中枢神经系统,在后脑有一个前界,并向后延伸到脊髓的尾部。在9.5~12.5天的胚胎中也观察到了相同的空间表达模式。这些结果表明,小鼠HOX1.5基因在胚胎发育过程中以空间受限的方式表达,类似于在果蝇减数分裂基因中观察到的模式。
The spatial pattern of expression of the murine homeo box-containing gene Hox 1.5 was studied during embryogenesis.In situhybridization of single-stranded RNA probes to mouse embryo sections revealed a specific spatial distribution of the Hox 1.5 transcripts in mouse embryos 8.5 to 12.5 days postcoitum (p.c.). Analysis of mouse embryos 8.5 days p.c. showed that the gene is expressed in a spatially restricted manner. Expression appears to be limited to the central nervous system with an anterior boundary in the hindbrain and extending posteriorly through caudal regions of the spinal cord. The same spatial pattern of expression was observed in embryos 9.5 to 12.5 days p.c. These results show that the murine Hox 1.5 gene is expressed in a spatially restricted manner during embryonic development similar to the patterns observed inDrosophilahomeotic genes.
DOI: 10.1038/321251a0
发表时间: 1986
期刊: Nature
影响因子: 64.8
作者:
P. Holland;B. Hogan
通讯作者: B. Hogan
哺乳动物同源盒基因。
DOI: 10.1101/sqb.1985.050.01.035
发表时间: 1985
期刊: Cold Spring Harbor symposia on quantitative biology
影响因子: --
作者:
Ruddle,FH;Hart,CP;Awgulewitsch,A;Fainsod,A;Utset,M;Dalton,D;Kerk,N;Rabin,M;Ferguson-Smith,A;Fienberg,A
通讯作者: Fienberg,A
小鼠同源盒基因在精母细胞和胚胎中表达。
DOI: --
发表时间: 1986
期刊: Science
影响因子: 56.9
作者:
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含有同源盒的基因在非节段海胆胚胎中的阶段特异性表达。
DOI: 10.1002/j.1460-2075.1986.tb04305.x
发表时间: 1986
期刊: The EMBO Journal
影响因子: --
作者:
G. Dolecki;Surawit Wannakrairojl;Richard Lum;Gordon Wang;Henry D. Riley;Ruben Carlos;Allan Wang;Tom Humphreys
通讯作者: Tom Humphreys
触角足类的同源框序列仅在高等动物基因组中保守。
DOI: --
发表时间: 1985
期刊: Cold Spring Harbor Symposia on Quantitative Biology
影响因子: --
作者:
W. McGinnis
通讯作者: W. McGinnis