Spastic reflexes triggered by ankle load release in human spinal cord injury.
Spastic reflexes triggered by ankle load release in human spinal cord injury.
复制标题
人类脊髓损伤中踝关节负荷释放引发的痉挛反射。
DOI：
10.1152/jn.00186.2006
复制
发表时间：
2006
影响因子：
2.5
通讯作者：
Schmit,BrianD
中科院分区：
文献类型：
--
作者：
Wu,Ming;Schmit,BrianD
负荷敏感的Ib组肌肉传入放电在卸载过程中的快速减少可能是特别重要的触发步态的摆动相。然而，目前仍不清楚负荷敏感性肌肉传入是否调节人类脊髓损伤（SCI）的反射活动，如猫的研究所示。12名慢性SCI患者的右髋关节使用自定义髋关节系统在40°屈曲至0-10°伸展的范围内进行斜坡（60°/s）和保持（10 s）运动。施加踝关节背屈载荷，并在髋关节达到目标位置后使用定制设计的气动马达系统释放。髋关节和膝关节的等距关节扭矩，踝关节的反应扭矩，和表面肌电图（EMG）从8个肌肉的腿被记录后施加的髋关节运动和踝关节负荷释放。当髋关节处于伸展位置时，踝关节负荷释放会触发以髋关节屈曲扭矩、膝关节伸展以及踝关节屈肌和伸肌共同激活为特征的反射。踝关节负荷释放被观察到，以增强髋关节伸展本身触发的反射，这表明踝关节负荷传入在人类SCI痉挛反射中起着重要作用，并且与踝关节负荷传入相关的反射通路在人类运动的脊髓反射调节中具有重要意义。这种肌肉行为强调踝关节负荷传入和髋关节本体感受器对运动的作用。这方面的知识可能是特别有帮助的痉挛的治疗，并在确定康复策略，以产生功能性运动在人类SCI。
The rapid decrease in firing of load-sensitive group Ib muscle afferents during unloading may be particularly important in triggering the swing phase of gait. However, it still remains unclear whether load-sensitive muscle afferents modulate reflex activity in human spinal cord injury (SCI), as suggested by studies in the cat. The right hip of 12 individuals with chronic SCI was subjected to ramp (60°/s) and hold (10 s) movements over a range from 40° flexion to 0–10°extension using a custom servomotor system. An ankle dorsiflexion load was imposed and released after the hip reached a targeted position using a custom-designed pneumatic motor system. Isometric joint torques of the hip and knee, reaction torque of the ankle, and surface electromyograms (EMGs) from eight muscles of the leg were recorded following the imposed hip movement and ankle load release. Reflexes, characterized by hip flexion torque, knee extension, and coactivation of ankle flexors and extensors, were triggered by ankle load release when the hip was in an extended position. The ankle load release was observed to enhance the reflexes triggered by hip extension itself, suggesting that ankle load afferents play an important role in spastic reflexes in human SCI and that the reflex pathways associated with ankle load afferents have important implications in the spinal reflex regulation of human movement. Such muscle behaviors emphasize the role of ankle load afferents and hip proprioceptors on locomotion. This knowledge may be especially helpful in the treatment of spasms and in identifying rehabilitation strategies for producing functional movements in human SCI.
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DOI：
--
发表时间：
1970
期刊：
Brain : a journal of neurology
影响因子：
--
作者：
M. Dimitrijevic;P. Nathan
通讯作者：
P. Nathan
影响因子：
11
作者：
DIMITRIJEVIC, MR;NATHAN, PW;SHERWOOD, AM
通讯作者：
SHERWOOD, AM
影响因子：
2.9
作者：
DUYSENS, J;PEARSON, KG
通讯作者：
PEARSON, KG
影响因子：
2.5
作者：
Lam, T;Pearson, KG
通讯作者：
Pearson, KG
DOI：
--
发表时间：
1976
期刊：
影响因子：
--
作者：
K. Pearson;J. Duysens
通讯作者：
J. Duysens