Presentation and Epidemiology of Gastroesophageal Reflux Disease.

Presentation and Epidemiology of Gastroesophageal Reflux Disease.
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DOI:
10.1053/j.gastro.2017.07.045
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发表时间:
2018-01
期刊:
影响因子:
29.4
通讯作者:
Rubenstein JH
Rubenstein JH
中科院分区:
医学1区
文献类型:
--
作者:
Richter JE;Rubenstein JH

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胃食管反流病(GERD)是美国最常见的胃肠道疾病,并导致大量的发病率,但相关的死亡率是罕见的。GERD症状的患病率似乎增加,直到1999年。GERD并发症的危险因素包括高龄、男性、白色人种、腹部肥胖和吸烟。大多数GERD患者表现为烧心和不费力的反流。同时存在的吞咽困难被认为是警报症状,提示评估。胃食管反流病的症状与嗜酸性食管炎、功能性消化不良和胃轻瘫的症状有很大的重叠,这对患者的管理提出了挑战。
Gastroesophageal reflux disease (GERD) is the most prevalent gastrointestinal disorder in the United States, and leads to substantial morbidity, though associated mortality is rare. The prevalence of GERD symptoms appeared to increase until 1999. Risk factors for complications of GERD include advanced age, male sex, white race, abdominal obesity, and tobacco use. Most patients with GERD presents with heartburn and effortless regurgitation. Coexistent dysphagia is considered an alarm symptom, prompting evaluation. There is substantial overlap between symptoms of GERD and those of eosinophilic esophagitis, functional dyspepsia, and gastroparesis, posing a challenge for patient management.
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