Detecting vascular biosignatures with a colloidal, radio-opaque polymeric nanoparticle.
Detecting vascular biosignatures with a colloidal, radio-opaque polymeric nanoparticle.
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DOI:
10.1021/ja906797z
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发表时间:
2009-10-28
影响因子:
15
通讯作者:
Lanza GM
中科院分区:
文献类型:
--
作者:
Pan D;Williams TA;Senpan A;Allen JS;Scott MJ;Gaffney PJ;Wickline SA;Lanza GM
A synthetic methodology for developing a polymeric nanoparticle for targeted computed tomographic (CT) imaging is revealed in this manuscript. The work describes a new class of “soft” type, vascularly constrained, stable colloidal radio-opaque metal-entrapped polymeric nanoparticle using organically soluble radio-opaque elements encapsulated by synthetic amphiphile. This agent offers several fold CT signal enhancement in vitro and in vivo demonstrating detection sensitivity reaching to the low nanomolar particulate concentration range.
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影响因子:
37.8
作者:
BROWN, BG;GALLERY, CA;DODGE, HT
通讯作者:
DODGE, HT
DOI:
10.1165/rcmb.2002-0028oc
发表时间:
2002-10-01
影响因子:
6.4
作者:
Avital, A;Shapiro, E;Springer, C
通讯作者:
Springer, C
影响因子:
4.8
作者:
Winter, Patrick M.;Schmieder, Anne H.;Lanza, Gregory M.
通讯作者:
Lanza, Gregory M.
DOI:
10.1002/3527603476.ch9
发表时间:
2005-01-01
期刊:
NANOFABRICATION TOWARDS BIOMEDICAL APPLICATIONS: TECHNIQUES, TOOLS, APPLICATIONS, AND IMPACT
影响因子:
--
作者:
Winter, Patrick M.;Caruthers, Shelton D.;Lanza, Gregory M.
通讯作者:
Lanza, Gregory M.
影响因子:
16.6
作者:
Nair, Shrikumar A.;Kolodziej, Andrew E.;Caravan, Peter
通讯作者:
Caravan, Peter