The carbapenem inactivation method (CIM), a simple and low-cost alternative for the Carba NP test to assess phenotypic carbapenemase activity in gram-negative rods.
The carbapenem inactivation method (CIM), a simple and low-cost alternative for the Carba NP test to assess phenotypic carbapenemase activity in gram-negative rods.
复制标题
DOI:
10.1371/journal.pone.0123690
复制
发表时间:
2015
期刊:
影响因子:
3.7
通讯作者:
Schouls LM
中科院分区:
文献类型:
--
作者:
van der Zwaluw K;de Haan A;Pluister GN;Bootsma HJ;de Neeling AJ;Schouls LM
A new phenotypic test, called the Carbapenem Inactivation Method (CIM), was developed to detect carbapenemase activity in Gram-negative rods within eight hours. This method showed high concordance with results obtained by PCR to detect genes coding for the carbapenemases KPC, NDM, OXA-48, VIM, IMP and OXA-23. It allows reliable detection of carbapenemase activity encoded by various genes in species of Enterobacteriaceae (e.g., Klebsiella pneumoniae, Escherichia coli and Enterobacter cloacae), but also in non-fermenters Pseudomonas aeruginosa and Acinetobacter baumannii. The CIM was shown to be a cost-effective and highly robust phenotypic screening method that can reliably detect carbapenemase activity.
登录
查看更多内容
DOI:
10.3904/kjim.2012.27.2.128
发表时间:
2012-06
期刊:
The Korean journal of internal medicine
影响因子:
--
作者:
Livermore DM
通讯作者:
Livermore DM
影响因子:
4.9
作者:
Jacoby, GA;Mills, DM;Chow, N
通讯作者:
Chow, N
影响因子:
5.2
作者:
Dallenne, Caroline;Da Costa, Anaelle;Arlet, Guillaume
通讯作者:
Arlet, Guillaume
影响因子:
4.9
作者:
Tijet, Nathalie;Boyd, David;Melano, Roberto G
通讯作者:
Melano, Roberto G
影响因子:
11.8
作者:
Nordmann P;Poirel L;Dortet L
通讯作者:
Dortet L