Overactive bladder symptom severity is associated with falls in community-dwelling adults: LOHAS study.
Overactive bladder symptom severity is associated with falls in community-dwelling adults: LOHAS study.
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DOI：
10.1136/bmjopen-2012-002413
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发表时间：
2013-05-03
期刊：
影响因子：
2.9
通讯作者：
Fukuhara S
中科院分区：
文献类型：
--
作者：
Kurita N;Yamazaki S;Fukumori N;Otoshi K;Otani K;Sekiguchi M;Onishi Y;Takegami M;Ono R;Horie S;Konno S;Kikuchi S;Fukuhara S
探讨膀胱过动症（OAB）症状严重程度与跌倒之间的关系，以及OAB症状对社区居住人群跌倒的影响。横断面研究。2个日本直辖市。共有2505名40岁以上居民参加了2010年进行的健康检查。通过膀胱过度活动症状评分（OABSS）评估OAB症状，根据分布和日本临床指南分为6类。活动能力问题和抑郁症状分别通过Timed Up and Go测试和流行病学研究中心抑郁量表的简短形式进行评估。自述1个月内有无跌倒或频繁跌倒（≥2次）。通过逻辑回归评估任何跌倒和频繁跌倒的独立因素，以产生人口归因分数（paf），假设OAB症状、行动能力问题和抑郁症状与任何跌倒或频繁跌倒之间存在单独的因果关系。在分析的1350名参与者（平均年龄：68.3岁）中，有跌倒和经常跌倒的比例分别为12.7%和4.4%。与无OABSS评分相比，中度至重度OAB和轻度OAB与任何跌倒相关（调整后的or分别为2.37 （95% CI 1.12至4.98）和2.51 (95% CI 1.14至5.52)）。中度至重度OAB也与频繁跌倒密切相关（调整后OR为6.90 (95% CI 1.50至31.6)）。任何跌倒的OAB症状的调整paf为40.7% (95% CI 0.7% - 64.6%)，频繁跌倒的调整paf为67.7% （95% CI - 23.1% - 91.5%）。此外，这些点估计值与行动能力问题和抑郁症状的估计值相似或更大。OAB症状严重程度与跌倒之间确实存在关联，OAB症状可能是社区居住成年人跌倒的重要因素。进一步的纵向研究是有必要的，以检查OAB症状是否预测未来跌倒和跌倒相关损伤的风险。
To examine the association between overactive bladder (OAB) symptom severity and falls and the contribution of OAB symptoms to falls in a community-dwelling population. Cross-sectional study. 2 Japanese municipalities. A total of 2505 residents aged over 40 years, who participated in health check-ups conducted in 2010. OAB symptom assessed via overactive bladder symptom score (OABSS) was divided into six categories based on distribution and Japanese clinical guidelines. Mobility problems and depressive symptoms were assessed via the Timed Up and Go test and the short form of the Center for Epidemiologic Studies Depression Scale, respectively. Self-reported any fall and frequent fall (≥2) over the 1-month period. Independent contributions to any fall and frequent falls were assessed via logistic regression to generate population-attributable fractions (PAFs), assuming separate causal relationships between OAB symptoms, mobility problems and depressive symptoms and any or frequent falls. Among the total 1350 participants (mean age: 68.3 years) analysed, any fall and frequent falls were reported by 12.7% and 4.4%, respectively. Compared with no OABSS score, moderate-to-severe OAB and mild OAB were associated with any fall (adjusted ORs 2.37 (95% CI 1.12 to 4.98) and 2.51 (95% CI 1.14 to 5.52), respectively). Moderate-to-severe OAB was also strongly associated with frequent falls (adjusted OR 6.90 (95% CI 1.50 to 31.6)). Adjusted PAFs of OAB symptoms were 40.7% (95% CI 0.7% to 64.6%) for any fall and 67.7% (95% CI −23.1% to 91.5%) for frequent falls. Further, these point estimates were similar to or larger than those of mobility problems and depressive symptoms. An association does indeed exist between OAB symptom severity and falls, and OAB symptoms might be important contributors to falls among community-dwelling adults. Further longitudinal studies are warranted to examine whether or not OAB symptoms predict risk of future falls and fall-related injuries.
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影响因子：
7.2
作者：
van Lersel, Marianne B.;Munneke, Marten;Rikkert, Marcel G. M. Olde
通讯作者：
Rikkert, Marcel G. M. Olde
影响因子：
23.4
作者：
Irwin, Debra E.;Milsom, Ian;Abrams, Paul
通讯作者：
Abrams, Paul
影响因子：
4.5
作者：
Homma, Y;Yamaguchi, O;Hayashi, K
通讯作者：
Hayashi, K
影响因子：
2.6
作者：
Vaughan CP;Brown CJ;Goode PS;Burgio KL;Allman RM;Johnson TM 2nd
通讯作者：
Johnson TM 2nd
DOI：
10.1111/j.1532-5415.1991.tb01616.x
发表时间：
1991-02-01
影响因子：
6.3
作者：
PODSIADLO, D;RICHARDSON, S
通讯作者：
RICHARDSON, S