Associations of dual sensory impairment with long-term depressive and anxiety symptoms in the United States.

Associations of dual sensory impairment with long-term depressive and anxiety symptoms in the United States.
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DOI:
10.1016/j.jad.2022.07.067
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发表时间:
2022-11-15
影响因子:
6.6
通讯作者:
Jones, Richard N.
Jones, Richard N.
中科院分区:
医学2区
文献类型:
--
作者:
Armstrong, Nicole M.;Teixeira, Camila Vieira Ligo;Gendron, Colby;Brenowitz, Willa D.;Lin, Frank R.;Swenor, Bonnelin;Powell, Danielle S.;Deal, Jennifer A.;Simonsick, Eleanor M.;Jones, Richard N.

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我们探讨了双重感觉障碍(DSI)与长期抑郁和焦虑症状的关联,以及低感知社会支持(LPSS)作为这些关联的调节因素。使用多项逻辑回归模型来检验DSI和单一感觉障碍(听力[纯音平均> 25 dB]和视力[视力和/或对比敏感性受损])与长期抑郁症状(10项流行病学研究中心抑郁量表≥8)和焦虑症状(霍普金斯症状检查表中存在)的关联,这些潜在类别来自基于群体的轨迹模型(罕见/从不;轻度/中度增加;在2102名健康、衰老和身体成分研究参与者(平均年龄:74.0±2.8岁;51.9%为女性)中,超过10年。根据人口统计学特征、心血管危险因素和LPSS对模型进行调整。另一个模型评估了DSI和LPSS之间的双向相互作用。DSI与慢性抑郁的风险增加相关(风险比,RR = 1.99, 95%可信区间,CI: 1.25, 3.17),而与轻度/中度加重抑郁无关(RR = 1.25, 95% CI: 0.91, 1.71)。与无损伤组相比,DSI组出现轻度/中度日益焦虑(RR = 1.60, 95% CI: 1.16, 2.19)和慢性焦虑(RR = 1.86, 95% CI: 1.05, 3.27)的风险增加。听力障碍与轻度/中度日益焦虑相关(RR = 1.34, 95% CI: 1.01, 1.79)。没有发现单一感觉障碍的其他关联。LPSS没有改变关联。感官测量是时间固定的,LPSS、抑郁和焦虑测量是自我报告的。未来的研究需要确定DSI疗法是否可以减轻长期的慢性高抑郁和焦虑症状。
We explored the associations of dual sensory impairment (DSI) with long-term depressive and anxiety symptoms as well as low perceived social support (LPSS) as a modifier of these associations. Multinomial logistic regression models were used to examine the associations of DSI and single sensory impairment (hearing [pure-tone average > 25 dB] and vision [impaired visual acuity and/or contrast sensitivity]) with long-term depressive symptom (≥8 on the 10-item Center for Epidemiologic Studies-Depression Scale) and anxiety symptom (present on the Hopkins Symptom Checklist) latent classes from group-based trajectory models (rare/never; mild/moderate increasing; chronically high) among 2102 Health, Aging and Body Composition Study participants (mean age:74.0 ± 2.8 years; 51.9 % female) over 10 years. Models were adjusted by demographic characteristics and cardiovascular risk factors, and LPSS. An additional model evaluated the two-way interaction between DSI and LPSS. DSI was associated with increased risk of being chronically depressed (Risk Ratio, RR = 1.99, 95 % Confidence Interval, CI: 1.25, 3.17), not mild/moderate increasingly depressed (RR = 1.25, 95 % CI: 0.91, 1.71). DSI had increased risk of being mild/moderate increasingly anxious (RR = 1.60, 95 % CI: 1.16, 2.19) and chronically anxious (RR = 1.86, 95 % CI: 1.05, 3.27) groups, as compared to no impairments. Hearing impairment was associated with being mild/moderate increasingly anxious (RR = 1.34, 95 % CI: 1.01, 1.79). No other associations were found for single sensory impairments. LPSS did not modify associations. Sensory measures were time-fixed, and LPSS, depression and anxiety measures were self-reported. Future research is warranted to determine if DSI therapies may lessen long-term chronically high depressive and anxiety symptoms.
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