The emerging role of dietary fructose in obesity and cognitive decline.
The emerging role of dietary fructose in obesity and cognitive decline.
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饮食果糖在肥胖症和认知能力下降中的新兴作用。
DOI：
10.1186/1475-2891-12-114
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发表时间：
2013-08-08
影响因子：
5.4
通讯作者：
Kirchgessner A
中科院分区：
文献类型：
--
作者：
Lakhan SE;Kirchgessner A
肥胖症的发病率在过去几年中急剧增加，与此同时，2型糖尿病（T2 D）的患病率也在增加。许多研究表明，肥胖和T2 D都与认知能力低下、认知能力下降和痴呆有关。膳食果糖的摄入量也有所增加。事实上，高果糖玉米糖浆（HFCS）占美国使用的热量甜味剂的40%。鉴于阿尔茨海默病（AD）发病率的增加，其特征是与年龄相关的记忆和认知功能下降，在本报告中，我们回顾了肥胖对认知能力的影响以及高果糖摄入对促进认知能力下降的影响。然后，该论文考虑了omega-3脂肪酸（FAs）的影响，这些脂肪酸与认知功能的有希望的结果有关，包括改善高果糖饮食的影响。
The incidence of obesity has increased dramatically over the past several years, and in parallel, so has the prevalence of type 2 diabetes (T2D). Numerous studies have demonstrated that both obesity and T2D are associated with lower cognitive performance, cognitive decline, and dementia. Intake of dietary fructose has also increased. In fact, high-fructose corn syrup (HFCS) accounts for as much as 40% of caloric sweeteners used in the United States. Given the increase in the incidence of Alzheimer’s disease (AD), characterized by an age-related decline in memory and cognitive functioning, in this report we review the effects of obesity on cognitive performance and the impact of high fructose intake in promoting cognitive decline. The paper then considers the effects of omega-3 fatty acids (FAs), which have been linked to promising results in cognitive function including ameliorating the impact of a high-fructose diet.
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影响因子：
5.5
作者：
Agrawal, Rahul;Gomez-Pinilla, Fernando
通讯作者：
Gomez-Pinilla, Fernando
影响因子：
9.9
作者：
Cournot, M.;Marquie, J. -C.;Ruidavets, J. -B.
通讯作者：
Ruidavets, J. -B.
影响因子：
--
作者：
Craft, S;Asthana, S;Veith, RC
通讯作者：
Veith, RC
影响因子：
3.7
作者：
Costello DA;Claret M;Al-Qassab H;Plattner F;Irvine EE;Choudhury AI;Giese KP;Withers DJ;Pedarzani P
通讯作者：
Pedarzani P
DOI：
10.1111/j.1752-8062.2011.00298.x
发表时间：
2011-08
期刊：
Clinical and translational science
影响因子：
--
作者：
Bremer AA;Stanhope KL;Graham JL;Cummings BP;Wang W;Saville BR;Havel PJ
通讯作者：
Havel PJ