Stem cells for augmenting tendon repair.
Stem cells for augmenting tendon repair.
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DOI:
10.1155/2012/291431
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发表时间:
2012
影响因子:
4.3
通讯作者:
Wiznia D
中科院分区:
文献类型:
--
作者:
Gulotta LV;Chaudhury S;Wiznia D
Tendon healing is fraught with complications such as reruptures and adhesion formation due to the formation of scar tissue at the injury site as opposed to the regeneration of native tissue. Stem cells are an attractive option in developing cell-based therapies to improve tendon healing. However, several questions remain to be answered before stem cells can be used clinically. Specifically, the type of stem cell, the amount of cells, and the proper combination of growth factors or mechanical stimuli to induce differentiation all remain to be seen. This paper outlines the current literature on the use of stem cells for tendon augmentation.
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