Diet Quality and Visceral Adiposity among a Multiethnic Population of Young, Middle, and Older Aged Adults.
Diet Quality and Visceral Adiposity among a Multiethnic Population of Young, Middle, and Older Aged Adults.
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DOI：
10.1093/cdn/nzaa090
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发表时间：
2020-06
影响因子：
4.8
通讯作者：
Shepherd JA
中科院分区：
文献类型：
--
作者：
Panizza CE;Wong MC;Kelly N;Liu YE;Shvetsov YB;Lowe DA;Weiss EJ;Heymsfield SB;Kennedy S;Boushey CJ;Maskarinec G;Shepherd JA
内脏性肥胖，比整体肥胖更与慢性疾病和死亡率相关。据我们所知，很少有研究探讨饮食质量和内脏脂肪组织（VAT）之间的关系，在18-80岁的多民族人群。这项横断面分析的主要目的是研究美国年轻、中年和老年人多种族人群的饮食质量[健康饮食指数-2010（HEI-2010）评分]与增值税之间的关联。次要目的是重复这些分析，将总体肥胖和2型糖尿病和心血管疾病风险的血液生物标志物作为结果指标。在3个研究中心（檀香山县、旧金山弗朗西斯科和巴吞鲁日）共招募了540名成年人（脱落：n = 4;年龄：18-40岁，n = 220; 40-60岁，n = 183; 60-80岁，n = 133）进行Shape Up！成人学习完成全身DXA、人体测量、空腹抽血和问卷调查（食物频率、体力活动和人口统计学特征）。线性回归用于评估HEI-2010三分位数和VAT之间的相关性，以及所有参与者和特定年龄层的次要结局指标，同时调整已知的混杂因素。VAT、BMI（kg/m2）、体脂百分比、总体脂、躯干脂肪、胰岛素和胰岛素抵抗与膳食质量呈负相关（P值均< 0.004）。当按年龄分层时，饮食质量与60-80岁参与者的VAT（P < 0.006）和40-60岁参与者的VAT/皮下脂肪组织（SAT）（P < 0.008）呈负相关。高质量的饮食与较低的VAT，总体肥胖和胰岛素抵抗在这个多种族人群中的年轻人，中年人和老年人，年龄从18岁到80岁。更具体地说，坚持高质量的饮食可以最大限度地减少60-80岁的成年人的增值税积累，并优先促进40-60岁的成年人与增值税相比，SAT的储存。本研究在clinicaltrials.gov上注册为NCT 03637855。
Visceral adiposity, more so than overall adiposity, is associated with chronic disease and mortality. There has been, to our knowledge, little research exploring the association between diet quality and visceral adipose tissue (VAT) among a mulitethnic population aged 18–80 y. The primary objective of this cross-sectional analysis was to examine the association between diet quality [Healthy Eating Index–2010 (HEI-2010) scores] and VAT among a multiethnic population of young, middle, and older aged adults in the United States. Secondary objectives were to repeat these analyses with overall adiposity and blood-based biomarkers for type 2 diabetes and cardiovascular disease risk as outcome measures. A total of 540 adults (dropped out: n = 4; age: 18–40 y, n = 220; 40–60 y, n = 183; 60–80 y, n = 133) were recruited across 3 sites (Honolulu County, San Francisco, and Baton Rouge) for the Shape Up! Adults study. Whole-body DXA, anthropometry, fasting blood draw, and questionnaires (food frequency, physical activity, and demographic characteristics) were completed. Linear regression was used to assess the associations between HEI-2010 tertiles and VAT and secondary outcome measures among all participants and age-specific strata, while adjusting for known confounders. VAT, BMI (kg/m2), body fat percentage, total body fat, trunk fat, insulin, and insulin resistance were inversely related to diet quality (all P values < 0.004). When stratified by age, diet quality was inversely associated with VAT among participants aged 60–80 y (P < 0.006) and VAT/subcutaneous adipose tissue (SAT) among participants aged 40–60 y (P < 0.008). Higher-quality diet was associated with lower VAT, overall adiposity, and insulin resistance among this multiethnic population of young, middle, and older aged adults with ages ranging from 18 to 80 y. More specifically, adherence to a high-quality diet may minimize VAT accumulation in adults aged 60–80 y and preferentially promote storage of SAT compared with VAT in adults aged 40–60 y. This study was registered at clinicaltrials.gov as NCT03637855.
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影响因子：
29.4
作者：
Lim, Unhee;Monroe, Kristine R.;Le Marchand, Loic
通讯作者：
Le Marchand, Loic
影响因子：
4.2
作者：
Dorn, JM;Hovey, K;Trevisan, M
通讯作者：
Trevisan, M
影响因子：
5
作者：
Kipnis, V;Subar, AF;Carroll, RJ
通讯作者：
Carroll, RJ
影响因子：
7.1
作者：
Harmon, Brook E.;Boushey, Carol J.;Kolonel, Laurence N.
通讯作者：
Kolonel, Laurence N.
影响因子：
16.2
作者：
Boyko, EJ;Fujimoto, WY;Newell-Morris, L
通讯作者：
Newell-Morris, L