The role of hyperpolarized (129)xenon in MR imaging of pulmonary function.

The role of hyperpolarized (129)xenon in MR imaging of pulmonary function.
复制标题

DOI:
10.1016/j.ejrad.2016.09.015
复制
发表时间:
2017-01
影响因子:
3.3
通讯作者:
Fain, Sean B.
Fain, Sean B.
中科院分区:
医学3区
文献类型:
--
作者:
Ebner, Lukas;Kammerman, Jeff;Driehuys, Bastiaan;Schiebler, Mark L.;Cadman, Robert V.;Fain, Sean B.

文献摘要

参考文献

被引文献

相似文献

在过去的二十年中,使用超极化惰性气体进行肺部功能成像已进入临床阶段。氦气 (3 He) 和氙气 (129Xe) 均已对其评估肺通气整体和区域模式的能力进行了彻底研究。随着偏振器技术的进步以及目前向广泛使用的 129Xe 气体的过渡,该方法已准备好应用于临床。目前,超极化(HP)惰性气体肺 MRI 仅限于选定的学术机构;然而,初步临床试验的有希望的结果引起了肺医学界的关注。 HP 129Xe MRI 不仅提供 3 维通气成像,还提供探测区域肺部生理学的独特功能。在这篇综述文章中,我们的目标是 (1) 简要概述当前的通气 MR 成像技术,(2) 强调 HP 129Xe MRI 在一系列不同成像策略中的作用,(3) 讨论 HP 129Xe MRI 的独特成像可能性,以及 (4) 提出临床应用。
In the last two decades, functional imaging of the lungs using hyperpolarized noble gases has entered the clinical stage. Both helium (3 He) and xenon (129Xe) gas have been thoroughly investigated for their ability to assess both the global and regional patterns of lung ventilation. With advances in polarizer technology and the current transition towards the widely available 129Xe gas, this method is ready for translation to the clinic. Currently, hyperpolarized (HP) noble gas lung MRI is limited to selected academic institutions; yet, the promising results from initial clinical trials have drawn the attention of the pulmonary medicine community. HP 129Xe MRI provides not only 3-dimensional ventilation imaging, but also unique capabilities for probing regional lung physiology. In this review article, we aim to (1) provide a brief overview of current ventilation MR imaging techniques, (2) emphasize the role of HP 129Xe MRI within the array of different imaging strategies, (3) discuss the unique imaging possibilities with HP 129Xe MRI, and (4) propose clinical applications.
DOI: 10.1016/j.acra.2005.08.005
发表时间: 2005-11-01
期刊: ACADEMIC RADIOLOGY
影响因子: 4.8
作者:
Fain, SB;Altes, TA;Owers-Bradley, J
通讯作者: Owers-Bradley, J
DOI: 10.1016/s0720-048x(98)00169-7
发表时间: 1999-03-01
影响因子: 3.3
作者:
Hatabu, H;Alsop, DC;Gefter, WB
通讯作者: Gefter, WB
DOI: 10.1378/chest.130.4.1055
发表时间: 2006-10-01
期刊: CHEST
影响因子: 9.6
作者:
de lange, Eduard E.;Altes, Talissa A.;Platts-Mills, Thomas A.
通讯作者: Platts-Mills, Thomas A.
DOI: 10.1007/s00247-012-2465-4
发表时间: 2013-03-01
影响因子: 2.3
作者:
Goo, Hyun Woo
通讯作者: Goo, Hyun Woo
DOI: 10.1148/radiol.11102172
发表时间: 2012-01-01
期刊: RADIOLOGY
影响因子: 19.7
作者:
Driehuys, Bastiaan;Martinez-Jimenez, Santiago;McAdams, H. Page
通讯作者: McAdams, H. Page