Evidence of high-risk sexual behaviors among injection drug users in the Kenya PLACE study.
Evidence of high-risk sexual behaviors among injection drug users in the Kenya PLACE study.
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DOI：
10.1016/j.drugalcdep.2011.05.030
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发表时间：
2011-12-01
影响因子：
4.2
通讯作者：
Weir S
中科院分区：
文献类型：
--
作者：
Brodish P;Singh K;Rinyuri A;Njeru C;Kingola N;Mureithi P;Sambisa W;Weir S
资源匮乏环境中的注射吸毒者（IDU）通过不安全的针头共享和性行为传播艾滋病毒的风险很高。我们报告的注射和性行为的样本注射吸毒者从马林迪，肯尼亚。2010年4月至5月进行了一项地方艾滋病控制工作重点研究，以确定最有可能发生艾滋病毒传播的地区和人们结识新性伴侣的具体场所。社区举报人（n=202）列出了157个独特的场地，其中29个是随机选择使用系统的固定间隔抽样策略与概率成比例的场地大小。在每个场地采访了20名顾客和4名工人。药物使用的做法引起了工作人员管理的采访。40%至50%的注射吸毒者报告说，在过去的一个月里，他们共用针头，从共同的容器中吸毒，使用现成的溶液而不煮沸，并且没有更换新的注射器。大多数人可能不一致或永远不会得到新的注射器。在控制年龄、教育、居住地和贫困状况的多变量logistic回归模型中，注射吸毒者报告过去一年有多个伴侣（OR 1.94，95%CI 1.26 - 3.00，p < .01）和过去一年有多个新伴侣（OR 2.11，95%CI 1.30 - 3.42，p < .01）的可能性是非注射吸毒者的两倍。在肯尼亚的马林迪，注射吸毒者中多个性伴侣和危险注射行为的高流行率以及新注射针头的缺乏可能促进了艾滋病毒的传播。
Injection drug users (IDUs) in resource poor settings are at high risk for HIV transmission through unsafe needle-sharing and sexual practices. We report on the injecting and sexual behavior of a sample of IDUs from Malindi, Kenya. A Priority for Local AIDS Control Efforts (PLACE) study was conducted from April to May 2010 to identify areas where HIV transmission is most likely to occur and specific venues where people meet new sexual partners. Community informants (n=202) listed 157 unique venues from which 29 were randomly selected using a systematic fixed interval sampling strategy with probability of selection proportional to venue size. Twenty patrons and four workers were interviewed at each venue. Drug use practices were elicited in a staff-administered interview. Between 40% and 50% of IDUs reported needle-sharing, taking drugs from a common reservoir, using a ready-made solution without boiling, and not exchanging a used for a new syringe in the past month. Most could inconsistently or never get new syringes. In multivariate logistic regression models controlling for age, education, residence, and poverty status, IDUs were twice as likely as non-IDUs to report multiple partners in the past year (OR 1.94, 95% CI 1.26 – 3.00, p < .01) and multiple new partners in the past year (OR 2.11, 95% CI 1.30 – 3.42, p < .01). High prevalence of multiple sexual partnerships and risky injecting behaviors among IDUs and unavailability of new injecting needles are likely facilitating HIV transmission in Malindi, Kenya.
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影响因子：
168.9
作者：
Mathers, Bradley M.;Degenhardt, Louisa;Mattick, Richard P.
通讯作者：
Mattick, Richard P.
DOI：
10.1016/s0140-6736(10)60743-x
发表时间：
2010-07-24
期刊：
Lancet (London, England)
影响因子：
--
作者：
Strathdee SA;Hallett TB;Bobrova N;Rhodes T;Booth R;Abdool R;Hankins CA
通讯作者：
Hankins CA
影响因子：
2.9
作者：
Beckerleg, SE;Hundt, GL
通讯作者：
Hundt, GL
影响因子：
4.4
作者：
Tate, Jackie;Singh, Kavita;Buckner, Bates
通讯作者：
Buckner, Bates
影响因子：
1.8
作者：
Williams, Mark L.;McCurdy, Sheryl A.;Leshabari, M. T.
通讯作者：
Leshabari, M. T.