A highly sensitive electrochemiluminescence method combined with molecularly imprinted solid phase extraction for the determination of phenolphthalein in drug, slimming food and human plasma
A highly sensitive electrochemiluminescence method combined with molecularly imprinted solid phase extraction for the determination of phenolphthalein in drug, slimming food and human plasma
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高灵敏电化学发光结合分子印迹固相萃取法测定药物、减肥食品和人血浆中的酚酞
DOI：
10.1016/j.foodchem.2011.11.056
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发表时间：
2012-05
期刊：
影响因子：
8.8
通讯作者：
Panpan Gai
中科院分区：
文献类型：
--
作者：
Zhiyong Guo;Lili Shi;Ning Gan;Tingting Hao;Sui Wang;Jing Duan;Panpan Gai
An electrochemiluminescence (ECL) inhibition method combined with molecularly imprinted solid phase extraction (MISPE) was developed for quantitative determination of phenolphthalein in drug, slimming food and human plasma. Phenolphthalein could strongly inhibit the ECL signal of Ru(bpy)32+/2-(dibutylamino)ethanol (DBAE) system that was used as the basis of the analysis. Molecularly imprinted polymers (MIPs) were synthesized as solid phase extraction (SPE) sorbents, and MISPE protocol was developed for the selective extraction and purification of phenolphthalein. Under the optimized conditions, quenched ECL intensity versus the logarithm of the concentration of phenolphthalein was in good linear relationship over a concentration range from 3.18×10−10to 1.59×10−7g/mL and the detection limit was 1.0×10−10g/mL. High affinity and selectivity of MISPE enabled the successful application of this method to determine phenolphthalein in drug, slimming food and human plasma. Further, a possible mechanism for the quenching effects of Ru(bpy)32+/DBAE system by phenolphthalein was also proposed.
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影响因子：
4.3
作者：
Cobb, Z;Andersson, LI
通讯作者：
Andersson, LI
DOI：
10.1039/a806379f
发表时间：
1998
期刊：
Analytical Communications
影响因子：
--
作者：
J. Olsen;Paul D. Martin;I. Wilson
通讯作者：
J. Olsen;Paul D. Martin;I. Wilson
影响因子：
7.4
作者：
Yuwu Chi;Yongqiang Dong;Guonan Chen
通讯作者：
Yuwu Chi;Yongqiang Dong;Guonan Chen
DOI：
10.1016/s0165-9936(04)00603-x
发表时间：
2004-06
期刊：
Trends in Analytical Chemistry
影响因子：
--
作者：
Xue-bo Yin;S. Dong;E. Wang
通讯作者：
Xue-bo Yin;S. Dong;E. Wang
DOI：
10.1002/bio.1135
发表时间：
2009-11
期刊：
Luminescence : the journal of biological and chemical luminescence
影响因子：
--
作者：
Jinghua Yu;Lei Ge;P. Dai;Congcong Zhang;Shenguang Ge;Jiadong Huang
通讯作者：
Jinghua Yu;Lei Ge;P. Dai;Congcong Zhang;Shenguang Ge;Jiadong Huang