Morphogenesis of denticles and hairs in Drosophila embryos: involvement of actin-associated proteins that also affect adult structures.
Morphogenesis of denticles and hairs in Drosophila embryos: involvement of actin-associated proteins that also affect adult structures.
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果蝇胚胎中小齿和毛发的形态发生:肌动蛋白相关蛋白的参与也影响成年结构。
DOI:
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发表时间:
1997
影响因子:
--
通讯作者:
John W. Thatcher
中科院分区:
文献类型:
--
作者:
W. J. Dickinson;John W. Thatcher
We sought components that function in morphogenetic events downstream from the segmentation pathway in Drosophila embryos, so we examined mutations that affect development of adult hairs and/or bristles to identify a subset that also affect hairs and denticles on the cuticle of first instar larvae. Mutations at 4 of 23 loci surveyed cause distinct abnormalities in these larval structures, and two other loci have more subtle, variable effects. In particular, forked and singed mutants produce complex, allele-specific phenotypes. These loci encode actin-associated proteins and, consistent with that information, mutations cause abnormalities in actin bundles that support nascent hairs and denticles in stage 14-16 embryos. We suggest that interactions between these and other actin-associated proteins are important in generating the diverse shapes of the cuticular specializations seen in both larvae and adults.
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DOI:
10.1073/pnas.90.11.4937
发表时间:
1993-06-01
影响因子:
11.1
作者:
APPEL, LF;PROUT, M;FRISTROM, J
通讯作者:
FRISTROM, J
DOI:
10.1242/dev.119.2.501
发表时间:
1993
期刊:
Development (Cambridge, England)
影响因子:
--
作者:
Bejsovec,A;Wieschaus,E
通讯作者:
Wieschaus,E
DOI:
10.1242/dev.120.4.717
发表时间:
1994
期刊:
Development (Cambridge, England)
影响因子:
--
作者:
Verheyen,EM;Cooley,L
通讯作者:
Cooley,L
DOI:
10.1073/pnas.90.19.9115
发表时间:
1993-10-01
影响因子:
11.1
作者:
BRYAN, J;EDWARDS, R;WULFKUHLE, J
通讯作者:
WULFKUHLE, J
影响因子:
3.3
作者:
Petersen,NS;Lankenau,DH;Mitchell,HK;Young,P;Corces,VG
通讯作者:
Corces,VG