Autopsy in dementing illness: who participates?

Autopsy in dementing illness: who participates?
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痴呆症尸检:谁参与?

DOI:
10.1097/00002093-199307020-00003
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发表时间:
1993
影响因子:
2.1
通讯作者:
Powers,R
Powers,R
中科院分区:
医学4区
文献类型:
--
作者:
Harrell,LE;Callaway,R;Powers,R

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各种类型的痴呆症的发生频率主要通过尸检系列来确定。由于尸检是自愿的,因此尚不清楚这些系列是否能代表整个痴呆人群。为了评估这个问题,我们对记忆障碍诊所五年内发生的所有死亡进行了审查,并对进行尸检和未尸检的患者之间的临床变量和诊断进行了比较。六十九名患者死亡; 43% (n= 30) 进行了尸检,57% (n= 39) 没有进行尸检。两组之间的种族(没有对黑人患者进行尸检)、发病年龄、就诊年龄、死亡年龄以及最后一次接触诊所和死亡之间的时间间隔(对于未进行尸检的患者明显较短)被发现存在差异。然而,两组的痴呆症临床诊断相似。 84% 的尸检患者的临床诊断得到证实。这些结果表明,尸检和非尸检患者的临床诊断之间没有重大差异,并且通过尸检系列获得的各种痴呆症的发生频率代表了痴呆人群。
The frequency of occurrence of various types of dementing disorders has been ascertained primarily from autopsied series. Since autopsy is voluntary, it is unknown if these series are representative of the entire demented population. To assess this issue, all deaths occurring over a 5-year period in our Memory Disorders Clinic were reviewed, and clinical variables and diagnoses were compared between patients who were autopsied and those who were not. Sixty-nine patients died; 43%(n= 30) underwent autopsy, and 57%(n= 39) did not. Race (no black patients were autopsied), age of disease onset, age of presentation to the clinic, age of death, and interval between last clinic contact and death (significantly less for nonautopsied patients) were found to differ between the two groups. However, clinical diagnosis of dementia was similar in the two groups. The clinical diagnosis was confirmed in 84% of autopsied patients. These results suggest that there are no major differences between clinical diagnoses for autopsied and nonautopsied patients and that the frequency of occurrence of various dementias obtained through autopsied series are representative of the demented population.
羔羊因氧气引起的肺损伤:人工通气的作用
DOI: --
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影响因子: 8.8
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