Type 2 diabetes mellitus and the risk of hepatitis C virus infection: a systematic review.
Type 2 diabetes mellitus and the risk of hepatitis C virus infection: a systematic review.
复制标题
2型糖尿病和丙型肝炎病毒感染的风险：系统评价。
DOI：
10.1038/srep02981
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发表时间：
2013-10-18
影响因子：
4.6
通讯作者：
Li JW
中科院分区：
文献类型：
--
作者：
Guo X;Jin M;Yang M;Liu K;Li JW
本研究的目的是评估2型糖尿病(T2 DM)与丙型肝炎病毒(丙型肝炎病毒)感染的关系，以及与普通人群的风险相比，T2 DM是否增加了丙型肝炎病毒感染的风险。我们遵循标准指南进行荟萃分析。根据确定的纳入标准选择相关文献。使用汇总优势比(OR)和95%可信区间(95%CI)来调查关联的强度。通过电子数据库和人工检索，确定了22项研究进行最终分析，总共包括78,051名个人。基于随机效应模型的Meta分析结果显示，T2 DM患者感染丙型肝炎病毒的风险高于非T2 DM患者(汇总OR=3.50，95%CI=2.54~4.82，I2=82.3%)。根据目前有限的证据，这项研究表明T2 DM与增加对丙型肝炎病毒感染的易感性有关。
The aim of this study was to evaluate the relationship between type 2 diabetes mellitus (T2DM) and hepatitis C virus (HCV) infection and to examine whether T2DM enhances the risk of HCV infection compared with the risk in the general population. We followed standard guidelines to perform a meta-analysis. The associated literature was selected based on the established inclusion criteria. The summary odds ratio (OR) and 95% confidence interval (95% CI) were used to investigate the strength of the association. Through electronic database and manual searching, 22 studies were identified for the final analysis, which included a total of 78,051 individuals. Based on the random effects model, the meta-analysis results showed that patients with T2DM were at a higher risk of acquiring HCV infection than non-T2DM patients (summary OR = 3.50, 95% CI = 2.54–4.82, I2 = 82.3%). Based on the current limited evidence, this study suggests that T2DM is associated with increased susceptibility to HCV infection.
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影响因子：
13.5
作者：
Mason, AL;Lau, JYN;Perrillo, RP
通讯作者：
Perrillo, RP
DOI：
10.1016/0197-2456(86)90046-2
发表时间：
1986-09-01
期刊：
CONTROLLED CLINICAL TRIALS
影响因子：
--
作者：
DERSIMONIAN, R;LAIRD, N
通讯作者：
LAIRD, N
影响因子：
29.4
作者：
Hui, JM;Sud, A;George, J
通讯作者：
George, J
影响因子：
105.7
作者：
Higgins, JPT;Thompson, SG;Altman, DG
通讯作者：
Altman, DG
影响因子：
4.5
作者：
Desenclos, JC;Bourdiol-Razès, M;Thiers, V
通讯作者：
Thiers, V