Association of dietary patterns with albuminuria and kidney function decline in older white women: a subgroup analysis from the Nurses' Health Study.
Association of dietary patterns with albuminuria and kidney function decline in older white women: a subgroup analysis from the Nurses' Health Study.
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DOI：
10.1053/j.ajkd.2010.09.027
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发表时间：
2011-02
期刊：
影响因子：
--
通讯作者：
Curhan GC
中科院分区：
文献类型：
--
作者：
Lin J;Fung TT;Hu FB;Curhan GC
饮食模式与心血管疾病等慢性疾病有关，但目前关于饮食模式与微量白蛋白尿或肾功能下降之间关系的数据很少。前瞻性观察队列研究的亚组分析护士健康研究的女性参与者的饮食模式数据来自1984年、1986年、1990年、1994年和1998年的食物频率问卷和2000年的尿白蛋白-肌酐比率（ACR） （n=3121）；肾小球滤过率（eGFR）在1989年至2000年间的变化可在1971年获得。谨慎（多摄入水果、蔬菜、豆类、鱼、家禽和全谷物）、西方（多摄入红肉和加工肉类、饱和脂肪和甜食）和“预防高血压饮食方法”（DASH）风格的饮食模式（也多摄入蔬菜、水果和全谷物）。2000年微量白蛋白尿（白蛋白与肌酐比值25至354mcg /mg）和1989年至2000年间eGFR对肾功能的影响。多变量调整后，Western模式评分最高四分位数与最低四分位数相比，与微量白蛋白尿（OR, 2.17; 95% CI, 1.18 ~ 3.66； p-for趋势=0.01）和eGFR快速下降≥3ml /min/1.73 m2 /年（OR, 1.77; 95% CI, 1.03 ~ 3.03）直接相关。DASH评分最高的四分之一的女性eGFR快速下降的风险降低（OR, 0.55; 95% CI， 0.38至0.80），但与微量白蛋白尿无关。这些关联与糖尿病状态无关。谨慎的饮食模式与微量白蛋白尿或eGFR下降无关。研究队列主要包括老年白人妇女，如果在非白人和男性中得到验证，结果的普遍性将受益。西方饮食模式与微量白蛋白尿和肾功能快速下降的风险显著升高有关，而dash风格的饮食模式可能对eGFR快速下降有保护作用。
Dietary patterns have been linked to chronic diseases such as cardiovascular disease, but sparse data are currently available on associations between dietary patterns and microalbuminuria or kidney function decline. Subgroup analysis from a prospective observational cohort study Female participants in the Nurses’ Health Study who had dietary patterns data from food frequency questionnaires returned in 1984, 1986, 1990, 1994, and 1998 and urinary albumin-creatinine ratios (ACR) from the year 2000 (n=3121); estimated glomerular filtration rate (eGFR) change between 1989 and 2000 was available in 3071. Prudent (higher intake of fruits, vegetables, legumes, fish, poultry, and whole grains), Western (higher intake of red and processed meats, saturated fats, and sweets), and Dietary Approach to Stop Hypertension (DASH) style dietary patterns (also greater intake of vegetables, fruits, and whole grains). Microalbuminuria (albumin-to-creatinine ratio 25 to 354 mcg/mg) in 2000 and change in kidney function by eGFR between 1989 and 2000. After multivariable adjustment, the highest quartile of Western pattern score compared to the lowest quartile was directly associated with microalbuminuria (OR, 2.17; 95% CI, 1.18 to 3.66; p-for trend=0.01) and rapid eGFR decline of ≥3 ml/min/1.73 m2 per year (OR, 1.77; 95% CI, 1.03 to 3.03). Women in the top quartile of the DASH score had decreased risk for rapid eGFR decline (OR, 0.55; 95% CI, 0.38 to 0.80), but had no association with microalbuminuria. These associations did not vary with diabetes status. The prudent dietary pattern was not associated with microalbuminuria or eGFR decline. Study cohort included primarily older white women and generalizability of results would benefit from validation in non-whites and men. A Western dietary pattern is associated with a significantly elevated risk for microalbuminuria and rapid kidney function decline whereas a DASH-style dietary pattern may be protective against rapid eGFR decline.
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DOI：
10.1053/j.ajkd.2008.10.044
发表时间：
2009-04
期刊：
American journal of kidney diseases : the official journal of the National Kidney Foundation
影响因子：
--
作者：
Bash LD;Erlinger TP;Coresh J;Marsh-Manzi J;Folsom AR;Astor BC
通讯作者：
Astor BC
影响因子：
--
作者：
Fung, TT;Willett, WC;Hu, FB
通讯作者：
Hu, FB
影响因子：
7.1
作者：
Lopez-Garcia, E;Schulze, MB;Hu, FB
通讯作者：
Hu, FB
影响因子：
--
作者：
Curhan, GC;Knight, EL;Stampfer, MJ
通讯作者：
Stampfer, MJ
影响因子：
39.2
作者：
Levey AS;Stevens LA;Schmid CH;Zhang YL;Castro AF 3rd;Feldman HI;Kusek JW;Eggers P;Van Lente F;Greene T;Coresh J;CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration)
通讯作者：
CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration)