Hospitalization and cognitive decline: Can the nature of the relationship be deciphered?
Hospitalization and cognitive decline: Can the nature of the relationship be deciphered?
复制标题
住院和认知能力下降：这种关系的本质能否被解读？
DOI：
10.1016/j.jagp.2012.08.012
复制
发表时间：
2014-05
影响因子：
7.2
通讯作者：
Epperson, C. Neill
中科院分区：
文献类型：
--
作者：
Mathews, Sarah B.;Arnold, Steven E.;Epperson, C. Neill
住院治疗与偶发性认知能力下降之间关系的证据主要存在于关注重症住院治疗的文献中。然而，最近的研究也发现非重症护理住院与认知能力下降的发展之间存在关联。本文将回顾有关住院治疗和认知能力下降的文献，包括重症和非重症住院治疗，以及内科和外科患者。本文还将探讨与认知能力下降和痴呆的发展有关的各种因素。使用PubMed和Medline搜索程序完成文献综述。有几篇文章支持住院治疗与认知能力下降之间的联系。潜在中介因素的证据也确实存在。有证据支持住院治疗与认知能力下降之间的联系。可能介导这种关联的因素包括但不限于谵妄、药物、压力和抑郁。为了更好地了解认知能力下降和痴呆发展的潜在病理生理学，并确定预防措施是否有助于降低住院患者认知能力下降的风险，需要在这一领域进行进一步的研究。
Evidence for a relationship between hospitalization and incident cognitive decline exists mainly in the literature focusing on critical care hospitalization. Recent studies, however, have also found an association between noncritical care hospitalization and the development of cognitive decline. This article will review the literature pertaining to hospitalization and cognitive decline, including hospitalizations for both critical and noncritical care, and in medical and surgical patients. The article will also explore the various factors that have been implicated in the development of cognitive decline and dementia. Review of the literature was completed using PubMed and Medline search programs. Several articles supporting evidence for the association between hospitalization and cognitive decline are available. Evidence for potential mediating factors also does exist. There is evidence to support an association between hospitalization and development of cognitive decline. Factors that could mediate this association include, but may not be limited to, delirium, medications, stress, and depression. There is a need for further research in this area in order to better understand the underlying pathophysiology involved in the development of cognitive decline and dementia and to determine if preventive measures might be beneficial in decreasing risk for cognitive decline for patients who are hospitalized.
登录
查看更多内容
影响因子：
6.6
作者：
Brown, E. Sherwood;Vera, Elizabeth;Johnson, Brandy
通讯作者：
Johnson, Brandy
影响因子：
2.4
作者：
Cherbuin, Nicolas;Reglade-Meslin, Chantal;Anstey, Kaarin J.
通讯作者：
Anstey, Kaarin J.
影响因子：
3.7
作者：
Christie, Jason D.;Biester, Rosette C. (Plotkin);Hopkins, Ramona O.
通讯作者：
Hopkins, Ramona O.
影响因子：
5.3
作者：
Coluccia, Daniel;Wolf, Oliver T.;de Quervain, Dominique J. -F.
通讯作者：
de Quervain, Dominique J. -F.
DOI：
10.1111/j.1532-5415.2004.52407.x
发表时间：
2004-09-01
影响因子：
6.3
作者：
Chodosh, J;Seeman, TE;Reuben, DB
通讯作者：
Reuben, DB