Imaging cellular distribution of fluorescent supramolecular nanofibers
Imaging cellular distribution of fluorescent supramolecular nanofibers
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荧光超分子纳米纤维的细胞分布成像
DOI:
10.1007/s11426-015-5521-8
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发表时间:
2016-06
影响因子:
9.6
通讯作者:
Yang Zhimou
中科院分区:
文献类型:
--
作者:
Wang Jingyu;Zheng Jing;Cai Yanbin;Zheng Jinxin;Gao Jie;Gong Qingqiu;Yang Zhimou
In this study, we used the 4-nitro-2,1,3-benzoxadiazole (NBD) as an aromatic capping group for a peptide to construct the supramolecular nanofibers. Taking the advantage of the fluorescence property of NBD, we could directly observe the cellular distribution of the self-assembled nanofibers. We found that the distributions of the nanofibers of NBD-FFETIGGY are different in four mammalian cells and two plant cells. The nanofibers are mainly located at the surface of two mammalian cells and one plant cell, while in the intracellular space of other cells. Different distributions of nanofibers lead to different protein binding patterns of the nanofibers in two different cell lines. We believe that a useful and versatile platform has been offered to the image cellular distribution of nanofibers, which can provide useful information to the biological functions of the self-assembled nanostructures.
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影响因子:
16.6
作者:
通讯作者:
--
影响因子:
56.9
作者:
Doyle, DA;Cabral, JM;MacKinnon, R
通讯作者:
MacKinnon, R
影响因子:
11.2
作者:
Standley SM;Toft DJ;Cheng H;Soukasene S;Chen J;Raja SM;Band V;Band H;Cryns VL;Stupp SI
通讯作者:
Stupp SI
影响因子:
15
作者:
Cheetham, Andrew G.;Zhang, Pengcheng;Lin, Yi-an;Lock, Lye Lin;Cui, Honggang
通讯作者:
Cui, Honggang
影响因子:
9.5
作者:
Huaimin Wang;Youzhi Wang;A. Han;Yanbin Cai;Nannan Xiao;Ling Wang;D. Ding;Zhimou Yang
通讯作者:
Huaimin Wang;Youzhi Wang;A. Han;Yanbin Cai;Nannan Xiao;Ling Wang;D. Ding;Zhimou Yang