Comparing Measures to Assess Health-Related Quality of Life in Heart Failure With Preserved Ejection Fraction.
Comparing Measures to Assess Health-Related Quality of Life in Heart Failure With Preserved Ejection Fraction.
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DOI：
10.1016/j.jchf.2018.02.006
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发表时间：
2018-07
期刊：
影响因子：
--
通讯作者：
Dunlay SM
中科院分区：
文献类型：
--
作者：
Napier R;McNulty SE;Eton DT;Redfield MM;AbouEzzeddine O;Dunlay SM
比较两种健康相关生活质量问卷在心力衰竭（HF）和射血分数保留（HFpEF）患者中的表现。准确评估随时间推移的HRQOL的能力在HF患者的护理中很重要。HRQOL工具包括明尼苏达心力衰竭生活质量问卷（MLHFQ）和堪萨斯城心肌病问卷（KCCQ）的有效性和可靠性尚未在HFpEF患者中完全确定或比较。在参加硝酸盐对心力衰竭活动耐量影响（NEAT）试验（n=110）的稳定慢性HFpEF患者中，我们评估并比较了基线、6周和12周MLHFQ和KCCQ变化的可靠性、有效性和反应性。MLHFQ和KCCQ领域在基线时测量HRQOL相似方面的内部一致性良好且相当，包括MLHFQ身体（Cronbach α=0.93）与KCCQ临床总结（α=0.91）相比，以及MLHFQ情感（α=0.92）与KCCQ生活质量（α=0.87）相比。基线时KCCQ总评分与NYHA心功能分级（斯皮尔曼rho; rs=-0.37 vs. 0.30）和6 MWT（rs =0.38 vs.-0.23）的相关性分别略强于MLHFQ总评分。MLHFQ对基于反应性统计的6 MWT变化的反应性更强。这些数据表明MLHFQ和KCCQ都是评估HFpEF患者HRQOL的可靠有效工具。KCCQ与基线功能状态参数的相关性更强，而MLHFQ对6 MWT的改善更敏感。
To compare the performance of two health-related quality of life questionnaires in patients with heart failure (HF) and preserved ejection fraction (HFpEF). The ability to accurately assess HRQOL over time is important in the care of patients with HF. The validity and reliability of HRQOL tools including the Minnesota Living with Heart Failure Questionnaire (MLHFQ) and the Kansas City Cardiomyopathy Questionnaire (KCCQ) has not been fully determined or compared in patients with HFpEF. Among patients with stable chronic HFpEF enrolled in the Nitrate Effect on Activity Tolerance in Heart Failure (NEAT) trial (n=110), we evaluated and compared reliability, validity, and responsiveness to change of the MLHFQ and KCCQ at baseline, 6 weeks, and 12 weeks. Internal consistency was good and comparable for MLHFQ and KCCQ domains measuring similar aspects of HRQOL at baseline including the MLHFQ physical (Cronbach’s α=0.93) compared to the KCCQ clinical summary (α=0.91), and the MLHFQ emotional (α=0.92) compared to the KCCQ quality of life (α=0.87). Correlations with NYHA functional class (Spearman rho; rs=−0.37 vs. 0.30) and 6MWT (rs =0.38 vs. −0.23) at baseline were slightly stronger for the KCCQ overall summary score than the MLHFQ total score, respectively. The MLHFQ was more responsive to change in 6MWT based on responsiveness statistics. These data suggest that both the MLHFQ and KCCQ are reliable and valid tools to assess HRQOL in HFpEF. The KCCQ was more strongly correlated with baseline functional status parameters, while the MLHFQ was more responsive to improvement in 6MWT.
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影响因子：
6
作者：
Holland, Richard;Rechel, Boika;Stepien, Karolina;Harvey, Ian;Brooksby, Iain
通讯作者：
Brooksby, Iain
影响因子：
4.6
作者：
Garin, Olatz;Herdman, Michael;Alonso, Jordi
通讯作者：
Alonso, Jordi
通过保留和减少的射血分数来预测心力衰竭：心力衰竭亚型的国际合作。
DOI：
10.1161/circheartfailure.115.003116
发表时间：
2016-06
期刊：
Circulation. Heart failure
影响因子：
--
作者：
Ho JE;Enserro D;Brouwers FP;Kizer JR;Shah SJ;Psaty BM;Bartz TM;Santhanakrishnan R;Lee DS;Chan C;Liu K;Blaha MJ;Hillege HL;van der Harst P;van Gilst WH;Kop WJ;Gansevoort RT;Vasan RS;Gardin JM;Levy D;Gottdiener JS;de Boer RA;Larson MG
通讯作者：
Larson MG
影响因子：
6
作者：
Luther, SA;McCullough, PA;Masoudi, FA
通讯作者：
Masoudi, FA
影响因子：
9.7
作者：
Rector, Thomas S.;Carson, Peter E.;Massie, Barry M.
通讯作者：
Massie, Barry M.