Intraoperative electrophysiological evaluations of macular function during peripheral scleral indentation.
Intraoperative electrophysiological evaluations of macular function during peripheral scleral indentation.
复制标题
DOI：
10.1038/srep35164
复制
发表时间：
2016-10-20
影响因子：
4.6
通讯作者：
Miyake Y
中科院分区：
文献类型：
--
作者：
Akiyama G;Matsumoto CS;Shinoda K;Terauchi G;Matsumoto H;Watanabe E;Iwata T;Mizota A;Miyake Y
巩膜压陷术被广泛用于检查周边眼底，但它会使眼内压（IOP）升高到很高的水平，从而影响视网膜功能。目的：评价巩膜压陷术对黄斑功能的电生理影响。术中记录7只眼在控制和不控制IOP的情况下的黄斑电图（iFMERG）。在未控制眼压的情况下，眼压从21.7 ± 4.9升至92.7 ± 20.2mmHg，（P = 0.020）和b波振幅（从6.29 ± 1.160到3.71 ± 1.98 uV，P = 0.007），明视负反应（从2.29 ± 0.99到0.72 ± 0.47 uV，on-PhNR，P = 0.005），和d波（从2.57 ± 0.41到1.64 ± 0.69 uV，P = 0.007）在开始压痕后不久显著降低。在释放缩进后，所有值均恢复到基线水平。在眼压控制的眼中，除了on-PhNR振幅在压陷期间显著降低外，眼压和所有分量的振幅在压陷期间和压陷后均无显著变化。巩膜凹陷引起的iFMERG和黄斑功能的变化是短暂的和可逆的。可以通过控制IOP来最小化变化。
Scleral indentation is widely used to examine the peripheral fundus, however it can increase the intraocular pressure (IOP) to high levels which can then affect retinal function. We evaluated the effects of scleral indentation on the macular function electrophysiologically. Intraoperative focal macular electroretinograms (iFMERGs) were recorded with and without controlling the IOP in 7 eyes. Without IOP control, the IOP increased from 21.7 ± 4.9 to 92.7 ± 20.2 mmHg significantly (P = 0.020) and the amplitudes of the b-wave (from 6.29 ± 1.160 to 3.71 ± 1.98 uV, P = 0.007), on-photopic negative response (from 2.29 ± 0.99 to 0.72 ± 0.47 uV, on-PhNR, P = 0.005), and d-wave (from 2.57 ± 0.41 to 1.64 ± 0.69 uV, P = 0.007) decreased significantly soon after beginning the indentation. All values returned to the baseline levels after releasing the indentation. In the eyes with IOP controlled, the IOP and the amplitude of all components did not change significantly during and after the indentation except the on-PhNR amplitude which was significantly reduced during the indentation. The changes in the iFMERGs and macular function caused by scleral indentation were transient and reversible. The changes can be minimized by controlling the IOP.
登录
查看更多内容
影响因子：
--
作者：
HORIGUCHI, M;MIYAKE, Y
通讯作者：
MIYAKE, Y
影响因子：
3.4
作者：
Kwong, Jacky M. K.;Vo, Nancy;Caprioli, Joseph
通讯作者：
Caprioli, Joseph
影响因子：
4.4
作者：
Kong, Yu X.;Crowston, Jonathan G.;Bui, Bang V.
通讯作者：
Bui, Bang V.
影响因子：
2
作者：
Findl, O;Strenn, K;Schmetterer, L
通讯作者：
Schmetterer, L
影响因子：
4.4
作者：
Fortune, B;Bui, BV;Cioffi, GA
通讯作者：
Cioffi, GA