Long-term impacts of ambient fine particulate matter exposure on overweight or obesity in Chinese adults: The China-PAR project.
Long-term impacts of ambient fine particulate matter exposure on overweight or obesity in Chinese adults: The China-PAR project.
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DOI：
10.1016/j.envres.2021.111611
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发表时间：
2021-10
影响因子：
8.3
通讯作者：
Gu, Dongfeng
中科院分区：
文献类型：
--
作者：
Huang, Sihan;Zhang, Xinyu;Liu, Zhongying;Liang, Fengchao;Li, Jianxin;Huang, Keyong;Yang, Xueli;Chen, Jichun;Liu, Xiaoqing;Cao, Jie;Chen, Shufeng;Shen, Chong;Yu, Ling;Zhao, Yingxin;Deng, Ying;Hu, Dongsheng;Huang, Jianfeng;Liu, Yang;Lu, Xiangfeng;Liu, Fangchao;Gu, Dongfeng
尽管新兴的研究已经将环境中的细颗粒物(PM2.5)与肥胖联系起来，但来自高污染地区的证据仍然缺乏。因此，我们评估了PM2.5对身体质量指数和超重/肥胖流行风险(BMI≥25 kg/m2)的长期影响，纳入了著名的中国动脉粥样硬化性心血管疾病风险预测(中国-PAR)项目，该项目包括77,609名参与者，并使用基于卫星的1公里空间分辨率PM2.5估计值。长期PM2.5值平均值为70.4μg/m~3，变化范围为32.1~94.2μg/m~3。PM2.5值每增加10μg/m~3，体重指数和超重/肥胖风险分别增加0.421 kg/m~2(95%可信区间：0.402，0.439)和13.5%(95%可信区间：12.8%，14.3%)。此外，与PM2.5的最低四分位数(≤57.5μg/m~3)相比，最高四分位数(>；85.9μg/m~3)超重/肥胖流行的相对风险为1.611(95%CI：1.566，1.657)。暴露-反应曲线表明PM2.5暴露与超重/肥胖之间存在非线性关系。此外，年龄、糖尿病、高血压和血脂异常状况也改变了这种关联。我们的研究为中国长期PM2.5对体重指数和超重/肥胖的不利影响提供了证据，研究结果对制定空气质量政策具有重要意义，特别是在污染严重的地区。
Although emerging researches have linked ambient fine particulate matter (PM2.5) to obesity, evidence from high-polluted regions is still lacking. We thus assessed the long-term impacts of PM2.5 on body mass index (BMI) and the risk of the prevalence of overweight/obesity (BMI≥25 kg/m2), by incorporating the well-established Prediction for Atherosclerotic Cardiovascular Disease Risk in China (China-PAR) project comprising 77,609 participants with satellite-based PM2.5 estimates at 1-km spatial resolution. The average of long-term PM2.5 level was 70.4 μg/m3, with the range of 32.1–94.2 μg/m3. Each 10 μg/m3 increment of PM2.5 was associated with 0.421 kg/m2 (95% confidence interval [CI]: 0.402, 0.439) and 13.5% (95% CI: 12.8%, 14.3%) increased BMI and overweight/obesity risk, respectively. Moreover, compared with the lowest quartile of PM2.5 (≤57.5 μg/m3), the relative risk of the prevalence of overweight/obesity from the highest quartile (>85.9 μg/m3) was 1.611 (95% CI: 1.566, 1.657). The exposure-response curve suggested a non-linear relationship between PM2.5 exposure and overweight/obesity. Besides, the association was modified by age, diabetes mellitus, hypertension and dyslipidemia status. Our study provides the evidence for the adverse impacts of long-term PM2.5 on BMI and overweight/obesity in China, and the findings are important for policy development on air quality, especially in severely polluted areas.
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DOI：
10.1016/s0140-6736(17)30505-6
发表时间：
2017-05-13
期刊：
Lancet (London, England)
影响因子：
--
作者：
Cohen AJ;Brauer M;Burnett R;Anderson HR;Frostad J;Estep K;Balakrishnan K;Brunekreef B;Dandona L;Dandona R;Feigin V;Freedman G;Hubbell B;Jobling A;Kan H;Knibbs L;Liu Y;Martin R;Morawska L;Pope CA 3rd;Shin H;Straif K;Shaddick G;Thomas M;van Dingenen R;van Donkelaar A;Vos T;Murray CJL;Forouzanfar MH
通讯作者：
Forouzanfar MH
影响因子：
2
作者：
DURRLEMAN, S;SIMON, R
通讯作者：
SIMON, R
DOI：
10.1016/s0140-6736(18)32225-6
发表时间：
2018-11-10
期刊：
Lancet (London, England)
影响因子：
--
作者：
GBD 2017 Risk Factor Collaborators
通讯作者：
GBD 2017 Risk Factor Collaborators
影响因子：
37.8
作者：
Sun Q;Yue P;Deiuliis JA;Lumeng CN;Kampfrath T;Mikolaj MB;Cai Y;Ostrowski MC;Lu B;Parthasarathy S;Brook RD;Moffatt-Bruce SD;Chen LC;Rajagopalan S
通讯作者：
Rajagopalan S
652个城市的环境颗粒物空气污染和每日死亡率
DOI：
10.1056/nejmoa1817364
发表时间：
2019-08-22
期刊：
The New England journal of medicine
影响因子：
--
作者：
Liu C;Chen R;Sera F;Vicedo-Cabrera AM;Guo Y;Tong S;Coelho MSZS;Saldiva PHN;Lavigne E;Matus P;Valdes Ortega N;Osorio Garcia S;Pascal M;Stafoggia M;Scortichini M;Hashizume M;Honda Y;Hurtado-Díaz M;Cruz J;Nunes B;Teixeira JP;Kim H;Tobias A;Íñiguez C;Forsberg B;Åström C;Ragettli MS;Guo YL;Chen BY;Bell ML;Wright CY;Scovronick N;Garland RM;Milojevic A;Kyselý J;Urban A;Orru H;Indermitte E;Jaakkola JJK;Ryti NRI;Katsouyanni K;Analitis A;Zanobetti A;Schwartz J;Chen J;Wu T;Cohen A;Gasparrini A;Kan H
通讯作者：
Kan H