Evaluation of Chemical Constituents of Litchi Pericarp Extracts and Its Antioxidant Activity in Mice.

Evaluation of Chemical Constituents of Litchi Pericarp Extracts and Its Antioxidant Activity in Mice.
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DOI:
10.3390/foods11233837
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发表时间:
2022-11-28
期刊:
Foods (Basel, Switzerland)
影响因子:
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其他
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荔枝果皮是荔枝加工的主要副产品,含有多种多酚类物质。然而,荔枝果皮提取物的化学成分及其抗氧化作用的研究却很少。对LPE中主要单体的定量分析结果表明,原花青素A2、原花青素B2、表儿茶素、芦丁和儿茶素是LPE中的主要多酚化合物。1,1-二苯基-2-苦基肼(DPPH)和抗坏血酸、2,2 ′-连氮基双-3-乙基苯并噻唑啉-6-磺酸(ABTS)的自由基清除活性表明,LPE具有较强的自由基清除活性。此外,D-半乳糖可导致小鼠体内抗氧化酶活性降低,脂质过氧化反应加剧,并诱导蛋白质氧化。在进行LPE治疗后,衰老小鼠的结果得到改善。上述结果表明,LPE具有优异的抗氧化作用。因此,荔枝果皮可以作为一个有前途的来源,膳食抗氧化剂。
Litchi pericarp is the main byproduct of litchi processing and contains several polyphenols. However, the chemical constituents and the antioxidant effect in litchi pericarp extracts (LPE) have been rarely studied. The result of the quantitative analyses of the major monomers in LPE indicated that procyanidin A2, procyanidin B2, epicatechin, rutin, and catechin were the major polyphenol compounds of LPE. The LPE exhibited high radical scavenging activity, as indicated by the results of the 1,1-diphenyl-2-picrylhydrazyl (DPPH) and ascorbic acid, 2,2′-Azinobis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) tests. Moreover, administrating D-galactose in mice led to the reduced activity of antioxidant enzymes, aggravated lipid peroxidation, and induced protein oxidation. The results were improved in the aging mice after the LPE treatment was performed. The above results suggest that LPE has an excellent antioxidant effect. Accordingly, litchi pericarp can serve as a promising source of dietary antioxidants.
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