Biometry of anterior segment of human eye on both horizontal and vertical meridians during accommodation imaged with extended scan depth optical coherence tomography.
Biometry of anterior segment of human eye on both horizontal and vertical meridians during accommodation imaged with extended scan depth optical coherence tomography.
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使用扩展扫描深度光学相干断层扫描对调节过程中人眼眼前节在水平和垂直经线上的生物测量进行成像。
DOI：
10.1371/journal.pone.0104775
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发表时间：
2014
期刊：
影响因子：
3.7
通讯作者：
Lu F
中科院分区：
文献类型：
--
作者：
Leng L;Yuan Y;Chen Q;Shen M;Ma Q;Lin B;Zhu D;Qu J;Lu F
目的：利用扩展扫描深度光学相干断层扫描（OCT）技术，测定调节过程中人眼水平和垂直子午线上眼前节尺寸的生物统计学特征。招募了20名年龄在24岁至30岁之间的老花眼前志愿者。使用扩展扫描深度OCT在水平和垂直子午线上的非和3.0屈光度（D）下对每个受试者的眼前段进行成像。分析所有图像以产生以下参数：瞳孔直径（PD）、前房深度（ACD）、晶体透镜的前表面和后表面曲率（ASC和PSC）以及透镜厚度（LT）。通过计算受试者内标准差（SD）、配对t检验、组内相关系数（ICC）和重复性/再现性系数（CoR），对OCT的重复性和再现性进行了连续两次测量。在两种不同的体位下，两次连续测量的水平和垂直经线之间的差异均无统计学意义（P>0.05）。所有参数的ICC范围从0.775到0.998，除了在非反射状态下水平子午线上的PSC（0.550）。此外，大多数参数的CoR均极佳（0.004%-4.89%）。在所有参数中，只有PD和PSC在两种状态下水平和垂直经络之间存在差异（P<0.05）。除垂直子午线上的PSC无变化外，直立状态下的PD、ACD、ASC和PSC均显著小于非直立状态下的PD、ACD、ASC和PSC。此外，调节时LT显著增加。扩展扫描深度OCT成功地测量了调节过程中前眼的尺寸，在水平和垂直子午线上具有良好的重复性和再现性。在调节过程中发现透镜后表面不对称，瞳孔呈椭圆形。
To determine the biometry of anterior segment dimensions of the human eye on both horizontal and vertical meridians with extended scan depth optical coherence tomography (OCT) during accommodation. Twenty pre-presbyopic volunteers, aged between 24 and 30, were recruited. The ocular anterior segment of each subject was imaged using an extended scan depth OCT under non- and 3.0 diopters (D) of accommodative demands on both horizontal and vertical meridians. All the images were analyzed to yield the following parameters: pupil diameter (PD), anterior chamber depth (ACD), anterior and posterior surface curvatures of the crystalline lens (ASC and PSC) and the lens thickness (LT). Two consecutive measurements were performed to assess the repeatability and reproducibility of this OCT. They were evaluated by calculating the within-subject standard deviation (SD), a paired t-test, intra-class correlation coefficients (ICC) and the coefficient of repeatability/reproducibility (CoR). There were no significant differences between two consecutive measurements on either horizontal or vertical meridians under both two different accommodative statuses (P>0.05). The ICC for all parameters ranged from 0.775 to 0.998, except for the PSC (0.550) on the horizontal meridian under the non-accommodative status. In addition, the CoR for most of the parameters were excellent (0.004% to 4.89%). In all the parameters, only PD and PSC were found different between the horizontal and vertical meridians under both accommodative statuses (P<0.05). PD, ACD, ASC and PSC under accommodative status were significantly smaller than those under the non-accommodative status, except that the PSC at the vertical meridian did not change. In addition, LT was significantly increased when accommodation. The extended scan depth OCT successfully measured the dimensions of the anterior eye during accommodation with good repeatability and reproducibility on both horizontal and vertical meridians. The asymmetry of lens posterior surface and oval-shaped pupil were found during accommodation.
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体内人类晶状体形貌。
影响因子：
3.4
作者：
Ortiz S;Pérez-Merino P;Gambra E;de Castro A;Marcos S
通讯作者：
Marcos S
影响因子：
2.9
作者：
GILMARTIN, B
通讯作者：
GILMARTIN, B
影响因子：
2.9
作者：
Charman, W. Neil;Radhakrishnan, Hema
通讯作者：
Radhakrishnan, Hema
影响因子：
2.8
作者：
Khanani, AM;Archer, SM;Brown, SM
通讯作者：
Brown, SM
DOI：
10.3928/15428877-20101031-08
发表时间：
2010-11-01
期刊：
Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye
影响因子：
--
作者：
Hurmeric, Volkan;Yoo, Sonia H;Culbertson, William W
通讯作者：
Culbertson, William W