Dietary magnesium intake and risk of metabolic syndrome: a meta-analysis.
Dietary magnesium intake and risk of metabolic syndrome: a meta-analysis.
复制标题
DOI：
10.1111/dme.12537
复制
发表时间：
2014-11
期刊：
影响因子：
--
通讯作者：
He K
中科院分区：
文献类型：
--
作者：
Dibaba DT;Xun P;Fly AD;Yokota K;He K
结合相关文献进行Meta分析，定量评价膳食镁摄入量与代谢综合征风险之间的关系。我们回顾了截至2013年8月发表的PubMed和EMBASE中的相关文献，并通过Google或手动检索相关文章中的参考文献获得了更多信息。一个随机效应或固定效应模型，适当的话，被用来汇总代谢综合征的影响大小，比较饮食镁摄入量最高的个体与摄入量最低的个体。评估镁摄入量每增加100 mg/天与代谢综合征风险的剂量反应关系。6个横断面研究，包括24 473个人和6311例代谢综合征，被确定为符合荟萃分析。膳食镁摄入量与代谢综合征风险之间存在加权负相关（比值比0.69，95%CI 0.59，0.81），最高组与最低组比较。镁摄入量每增加100毫克/天，患代谢综合征的总体风险降低17%（比值比0.83，95%CI 0.05）。77，0.89）。本荟萃分析的结果表明，膳食镁摄入量与代谢综合征的患病率呈负相关。需要进一步的研究，特别是设计良好的纵向队列研究和随机安慰剂对照临床试验，以提供可靠的证据并建立因果关系。
To estimate quantitatively the association between dietary magnesium intake and risk of metabolic syndrome by combining the relevant published articles using meta-analysis. We reviewed the relevant literature in PubMed and EMBASE published up until August 2013 and obtained additional information through Google or a hand search of the references in relevant articles. A random-effects or fixed-effects model, as appropriate, was used to pool the effect sizes on metabolic syndrome comparing individuals with the highest dietary magnesium intake with those having the lowest intake. The dose–response relationship was assessed for every 100-mg/day increment in magnesium intake and risk of metabolic syndrome. Six cross-sectional studies, including a total of 24 473 individuals and 6311 cases of metabolic syndrome, were identified as eligible for the meta-analysis. A weighted inverse association was found between dietary magnesium intake and the risk of metabolic syndrome (odds ratio 0.69, 95% CI 0.59, 0.81) comparing the highest with the lowest group. For every 100-mg/day increment in magnesium intake, the overall risk of having metabolic syndrome was lowered by 17% (odds ratio 0.83, 95% CI 0. 77, 0.89). Findings from the present meta-analysis suggest that dietary magnesium intake is inversely associated with the prevalence of metabolic syndrome. Further studies, in particular well-designed longitudinal cohort studies and randomized placebo-controlled clinical trials, are warranted to provide solid evidence and to establish causal inference.
登录
查看更多内容
影响因子：
5
作者：
GREENLAND, S;LONGNECKER, MP
通讯作者：
LONGNECKER, MP
影响因子：
7.2
作者：
Guerrero-Romero, F;Tamez-Perez, HE;Rodríguez-Morán, M
通讯作者：
Rodríguez-Morán, M
影响因子：
15.9
作者：
DANGELO, EKG;SINGER, HA;REMBOLD, CM
通讯作者：
REMBOLD, CM
影响因子：
3.6
作者：
Kishimoto, Yoshimi;Tani, Mariko;Kondo, Kazuo
通讯作者：
Kondo, Kazuo
影响因子：
6.9
作者：
Ford, Earl S.;Li, Chaoyang;Liu, Simin
通讯作者：
Liu, Simin