Plasma Metabolomics Reveals β-Glucan Improves Muscle Strength and Exercise Capacity in Athletes.
Plasma Metabolomics Reveals β-Glucan Improves Muscle Strength and Exercise Capacity in Athletes.
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DOI：
10.3390/metabo12100988
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发表时间：
2022-10-18
期刊：
影响因子：
4.1
通讯作者：
Wang R
中科院分区：
文献类型：
--
作者：
Wang R;Wu X;Lin K;Guo S;Hou Y;Ma R;Wang Q;Wang R
本研究旨在评估运动员补充β-葡聚糖后肌肉力量和血浆代谢物的变化。本研究共招募了29名符合入选标准的运动员（ChiCTR 2200058091），并随机分为安慰剂组（n = 14）和β-葡聚糖组（n = 15）。在试验期间，实验组接受为期4周的β-葡聚糖补充（2 g/d β-葡聚糖），对照组接受相同剂量的安慰剂补充（0 g/d β-葡聚糖），两组在试验期间均保持正常的饮食和运动习惯。在补充β-葡聚糖4周后，分析运动员的运动成绩、肌肉力量和血浆代谢组学变化。结果显示，与干预前相比，干预4周后实验组的平均握力（kg）、右手握力（kg）、左三头肌力量（kg）和上肢肌肉质量（kg）显著增加（p < 0.05）。干预后两组差异比较显示，对照组与实验组平均握力（kg）和右手握力（kg）差异有统计学意义（p < 0.05）。实验组运动员1 min双摇跳次数（pcs）、最大摄氧量（ml/kg-min）明显提高（p < 0.05）。β-葡聚糖摄入增加了血浆中肌酸相关途径的代谢物。总的来说，这些结果表明，4周的β-葡聚糖补充剂可以提高运动员的肌肉力量，有可能通过影响肌酸相关途径来提高有氧耐力和增强免疫功能。
The present study aimed to assess the changes in muscle strength and plasma metabolites in athletes with β-glucan supplementation. A total of 29 athletes who met the inclusion criteria were recruited for this study (ChiCTR2200058091) and were randomly divided into a placebo group (n = 14) and β-glucan group (n = 15). During the trial, the experimental group received β-glucan supplementation (2 g/d β-glucan) for 4 weeks and the control group received an equal dose of placebo supplementation (0 g/d β-glucan), with both groups maintaining their regular diet and exercise habits during the trial. The athletes’ exercise performance, muscle strength, and plasma metabolome changes were analyzed after 4 weeks of β-glucan supplementation. The results showed a significant increase in mean grip strength (kg), right hand grip strength (kg), left triceps strength (kg), and upper limb muscle mass (kg) in the experimental group after the 4-week intervention compared to the preintervention period (p < 0.05). A comparison of the difference between the two groups after the intervention showed that there were significant differences between the control group and the experimental group in mean grip strength (kg) and right-hand grip strength (kg) (p < 0.05). Athletes in the experimental group showed significant improvements in 1 min double rocking jump (pcs), VO2max (ml/kg-min) (p < 0.05). The β-glucan intake increased the creatine-related pathway metabolites in plasma. Overall, these results suggest that 4 weeks of β-glucan supplementation can improve muscle strength in athletes, with the potential to increase aerobic endurance and enhance immune function, possibly by affecting creatine-related pathways.
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影响因子：
2.4
作者：
Chilibeck PD;Kaviani M;Candow DG;Zello GA
通讯作者：
Zello GA
影响因子：
4
作者：
Damilakis, J.;Solomou, G.;Karantanas, A.
通讯作者：
Karantanas, A.
影响因子：
2.4
作者：
Mah, Eunice;Kaden, Valerie N.;Liska, DeAnn J.
通讯作者：
Liska, DeAnn J.
DOI：
10.3390/jof6040356
发表时间：
2020-12-10
期刊：
Journal of fungi (Basel, Switzerland)
影响因子：
--
作者：
Murphy EJ;Rezoagli E;Major I;Rowan NJ;Laffey JG
通讯作者：
Laffey JG
影响因子：
4.1
作者：
Lee MC;Jhang WL;Lee CC;Kan NW;Hsu YJ;Ho CS;Chang CH;Cheng YC;Lin JS;Huang CC
通讯作者：
Huang CC