Measuring health-related quality of life in population-based studies of coronary heart disease: comparing six generic indexes and a disease-specific proxy score.
Measuring health-related quality of life in population-based studies of coronary heart disease: comparing six generic indexes and a disease-specific proxy score.
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DOI：
10.1007/s11136-009-9533-8
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发表时间：
2009-11
影响因子：
3.5
通讯作者：
Fryback, Dennis G.
中科院分区：
文献类型：
--
作者：
Garster, Noelle C.;Palta, Mari;Sweitzer, Nancy K.;Kaplan, Robert M.;Fryback, Dennis G.
在美国成年人的全国代表性样本中，比较HRQoL与CHD在通用指标和代表性CVD特异性评分方面的差异。国家健康测量研究是一项针对35-89岁成人的横断面随机数字拨号电话调查，采用EQ-5D、QWB-SA、HUI 2、HUI 3、SF-36 v2 ™（产生PCS、MCS和SF-6D）和HALex。分析比较了3，350例无冠心病（第1组），265例未服用胸痛药物的冠心病（第2组）和218例目前服用胸痛药物的冠心病（第3组），调整和不调整人口统计学变量和合并症。来自心力衰竭诊所的154例患者的数据被用于利用探测CVD症状的通用项目构建代理评分。冠心病组间所有指标的平均评分在校正和未校正时均存在差异（除MCS外，所有指标均P < 0.0001，P = 0.018）。未校正的组3与组1的差异比组2与组1的差异大约3倍。代理评分的标准化差异与通用指数的标准化差异相似，除第3组与第1组的MCS外，所有指标的标准化差异均约为1.0。通用指数捕获的差异，HRQoL在人群为基础的研究，类似于一个分数构建的问题，探索心血管疾病的具体症状。
To compare HRQoL differences with CHD in generic indexes and a proxy CVD-specific score in a nationally representative sample of U.S. adults. The National Health Measurement Study, a cross-sectional random-digit-dialed telephone survey of adults aged 35–89, administered the EQ-5D, QWB-SA, HUI2, HUI3, SF-36v2™ (yielding PCS, MCS, and SF-6D), and HALex. Analyses compared 3,350 without CHD (group 1), 265 with CHD not taking chest pain medication (group 2), and 218 with CHD currently taking chest pain medication (group 3), with and without adjustment for demographic variables and comorbidities. Data on 154 patients from heart failure clinics were used to construct a proxy score utilizing generic items probing CVD symptoms. Mean scores differed between CHD groups for all indexes with and without adjustment (P < 0.0001 for all except MCS P = 0.018). Unadjusted group 3 versus 1 differences were about three times larger than for group 2 versus 1. Standardized differences for the proxy score were similar to those for generic indexes, and were about 1.0 for all except MCS for group 3 versus 1. Generic indexes capture differences in HRQoL in population-based studies of CHD similarly to a score constructed from questions probing CVD-specific symptoms.
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影响因子：
3.6
作者：
Horsman J;Furlong W;Feeny D;Torrance G
通讯作者：
Torrance G
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